Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using GPS1 antibody.)
Rabbit GPS1 Polyclonal Antibody | anti-GPS1 antibody
GPS1 Polyclonal Antibody
Gene Names
GPS1; CSN1; SGN1; COPS1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
GPS1; Polyclonal Antibody; GPS1 Polyclonal Antibody; COP9 signalosome complex subunit 1; SGN1; Signalosome subunit 1; G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH; COPS1; CSN1; anti-GPS1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
GPS1 polyclonal antibody detects endogenous levels of GPS1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
491
Applicable Applications for anti-GPS1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
IHC: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant full length Human GPS1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using GPS1 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using GPS1 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U20S cell using GPS1 antibody. Blue: DAPI for nuclear staining.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U20S cell using GPS1 antibody. Blue: DAPI for nuclear staining.)
Related Product Information for anti-GPS1 antibody
This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 56kDa
NCBI Official Full Name
COP9 signalosome complex subunit 1 isoform 2
NCBI Official Synonym Full Names
G protein pathway suppressor 1
NCBI Official Symbol
GPS1
NCBI Official Synonym Symbols
CSN1; SGN1; COPS1
NCBI Protein Information
COP9 signalosome complex subunit 1
UniProt Protein Name
COP9 signalosome complex subunit 1
UniProt Gene Name
GPS1
UniProt Synonym Gene Names
COPS1; CSN1; SGN1; Signalosome subunit 1; GPS-1
UniProt Entry Name
CSN1_HUMAN
NCBI Description
This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. [provided by RefSeq, Mar 2016]
Uniprot Description
COPS1: a protein that suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. Shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells.
Protein type: G protein regulator, misc.
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: signalosome; cytoplasm; nucleus
Molecular Function: protein binding; GTPase inhibitor activity
Biological Process: cullin deneddylation; JNK cascade; cell cycle; inactivation of MAPK activity
Research Articles on GPS1
Similar Products
Product Notes
The GPS1 gps1 (Catalog #AAA3011839) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPS1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the GPS1 gps1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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