Rabbit anti-Human GPRC5B Polyclonal Antibody | anti-GPRC5B antibody
GPRC5B antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Uniprot Description
GPRC5B: Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family.
Protein type: Receptor, GPCR; GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16p12
Cellular Component: extracellular space; cytoplasmic vesicle membrane; cell surface; intracellular membrane-bound organelle; nucleolus; integral to membrane; plasma membrane; nucleus; lipid raft
Molecular Function: G-protein coupled receptor activity; G-protein-coupled receptor binding; protein kinase binding; protein kinase activator activity
Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; locomotory behavior; positive regulation of neuron differentiation; glucose homeostasis; positive regulation of inflammatory response
Research Articles on GPRC5B
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Product Notes
The GPRC5B gprc5b (Catalog #AAA535590) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPRC5B antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPRC5B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. IHC-P: 20 ug/ml. Researchers should empirically determine the suitability of the GPRC5B gprc5b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPRC5B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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