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Immunohistochemistry (IHC) (Anti-GPR4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit GPR4 Polyclonal Antibody | anti-GPR4 antibody

Rabbit Polyclonal to Human GPR4

Reactivity
Gibbon, Dog, Human, Monkey, Pig
Predicted Reactivity: Bat, Bovine, Rabbit, Zebrafish (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, Immunocytochemistry
Purity
Immunoaffinity Purified
Synonyms
GPR4; Polyclonal Antibody; Rabbit Polyclonal to Human GPR4; Anti-GPR4 Antibody (Cytoplasmic Domain) IHC-plus; G-protein coupled receptor 19; G-protein coupled receptor 4; Gpr6c; G protein-coupled receptor 4; Human GPR4; anti-GPR4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Dog, Human, Monkey, Pig
Predicted Reactivity: Bat, Bovine, Rabbit, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human GPR4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
362
Applicable Applications for anti-GPR4 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC)
Application Notes
ICC, IHC-P (15 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR4. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Dog, Panda, Pig (100%); Bovine, Bat, Rabbit, Zebrafish (95%); Mouse, Rat (85%).
Immunogen Type
Synthetic peptide
Immunogen
GPR4 antibody was raised against synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR4. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Dog, Panda, Pig (100%); Bovine, Bat, Rabbit, Zebrafish (95%); Mouse, Rat (85%).
Antigen Modification
Cytoplasmic Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-GPR4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GPR4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR4 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GPR4 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GPR4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-GPR4 antibody
GPR4 is a Lysophospholipid/Lysosphingolipid receptor. Recently, GPR4 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003).
Product Categories/Family for anti-GPR4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,982 Da
NCBI Official Full Name
G-protein coupled receptor 4
NCBI Official Synonym Full Names
G protein-coupled receptor 4
NCBI Official Symbol
GPR4
NCBI Protein Information
G-protein coupled receptor 4; G-protein coupled receptor 19
UniProt Protein Name
G-protein coupled receptor 4
UniProt Gene Name
GPR4
UniProt Synonym Gene Names
GPR19
UniProt Entry Name
GPR4_HUMAN

Uniprot Description

GPR4: Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on GPR4

Similar Products

Product Notes

The GPR4 gpr4 (Catalog #AAA244318) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GPR4 reacts with Gibbon, Dog, Human, Monkey, Pig Predicted Reactivity: Bat, Bovine, Rabbit, Zebrafish (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's GPR4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC). ICC, IHC-P (15 ug/ml). Researchers should empirically determine the suitability of the GPR4 gpr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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