Rabbit anti-Human GPR37L1 Polyclonal Antibody | anti-GPR37L1 antibody

GPR37L1, NT (GPR37L1, ETBRLP2, Endothelin B receptor-like protein 2, G-protein coupled receptor 37-like 1) (PE)

Cat. Num. AAA6303930

• Gene Names: GPR37L1; ETBR-LP-2; ET(B)R-LP-2
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GPR37L1; Polyclonal Antibody; NT (GPR37L1; ETBRLP2; Endothelin B receptor-like protein 2; G-protein coupled receptor 37-like 1) (PE); G-protein coupled receptor 37-like 1; anti-GPR37L1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-GPR37L1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GPR37L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from the N-terminal region of human GPR37L1.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GPR37L1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GPR37L1 antibody detected the GPR37L1 protein (arrow).)

Product Categories/Family for anti-GPR37L1 antibody

Antibodies; Endotoxin

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010). Arking, D.E., et al. PLoS ONE 5 (3), E9879 (2010): Valdenaire, O., et al. FEBS Lett. 424(3):193-196(1998).

NCBI and Uniprot Product Information

• NCBI GI #: 134244291
• NCBI GeneID: 9283
• NCBI Accession #: NP_004758.3
• NCBI GenBank Nucleotide #: NM_004767.3
• UniProt Accession #: O60883; Q5SXP7; Q86VP7
• Molecular Weight: 52,771 Da
• NCBI Official Full Name: endothelin B receptor-like protein 2
• NCBI Official Synonym Full Names: G protein-coupled receptor 37 like 1
• NCBI Official Symbol: GPR37L1
• NCBI Official Synonym Symbols: ETBR-LP-2; ET(B)R-LP-2
• NCBI Protein Information: endothelin B receptor-like protein 2; G-protein coupled receptor 37 like 1; G-protein coupled receptor 37-like 1; endothelin type b receptor-like protein 2
• UniProt Protein Name: Endothelin B receptor-like protein 2
• Protein Family: Prosaposin receptor
• UniProt Gene Name: GPR37L1
• UniProt Synonym Gene Names: ETBRLP2; ETBR-LP-2
• UniProt Entry Name: ETBR2_HUMAN

Uniprot Description

GPR37L1: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: plasma membrane; integral to membrane; receptor complex

Molecular Function: protein binding; peptide receptor activity, G-protein coupled; peptide binding

Biological Process: negative regulation of neuron differentiation; positive regulation of MAPKKK cascade; negative regulation of smoothened signaling pathway; negative regulation of astrocyte differentiation; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of granule cell precursor proliferation