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Immunohistochemistry (IHC) (Anti-GPR35 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit GPR35 Polyclonal Antibody | anti-GPR35 antibody

Rabbit Polyclonal to Human GPR35

Reactivity
Gibbon, Gorilla, Human
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
GPR35; Polyclonal Antibody; Rabbit Polyclonal to Human GPR35; Anti-GPR35 Antibody (Extracellular Domain) IHC-plus; KYNA receptor; Kynurenic acid receptor; G protein-coupled receptor 35; G-protein coupled receptor 35; Human GPR35; anti-GPR35 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human
Clonality
Polyclonal
Specificity
Human GPR35. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
309
Applicable Applications for anti-GPR35 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (9 - 22 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from 3rd extracellular domain of human GPR35. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (83%).
Immunogen Type
Synthetic peptide
Immunogen
GPR35 antibody was raised against synthetic 18 amino acid peptide from 3rd extracellular domain of human GPR35. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (83%).
Antigen Modification
Extracellular Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-GPR35 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GPR35 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-GPR35 antibody
GPR35 is an Orphan-A GPCR with an unknown ligand.
Product Categories/Family for anti-GPR35 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,452 Da
NCBI Official Full Name
G-protein coupled receptor 35 isoform a
NCBI Official Synonym Full Names
G protein-coupled receptor 35
NCBI Official Symbol
GPR35
NCBI Protein Information
G-protein coupled receptor 35; KYNA receptor; kynurenic acid receptor
UniProt Protein Name
G-protein coupled receptor 35
UniProt Gene Name
GPR35
UniProt Synonym Gene Names
KYNA receptor
UniProt Entry Name
GPR35_HUMAN

Uniprot Description

GPR35: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on GPR35

Similar Products

Product Notes

The GPR35 gpr35 (Catalog #AAA243617) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GPR35 reacts with Gibbon, Gorilla, Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPR35 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (9 - 22 ug/ml). Researchers should empirically determine the suitability of the GPR35 gpr35 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR35, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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