anti-Rat GPR14 Polyclonal Antibody | anti-GPR14 antibody
Anti - GPR14 (UII Receptor)
Gene Names
UTS2R; UTR; UTR2; GPR14; UR-2-R
Reactivity
Rat
Applications
ELISA
Purity
Purified by immunoaffinity chromatography.
Synonyms
GPR14; Polyclonal Antibody; Anti - GPR14 (UII Receptor); GPR14 (UII Receptor); anti-GPR14 antibody
Host
Host: Rabbit
Source: Rat
Source: Rat
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
The rat control peptide sequence is 93% conserved in mouse, 77% in human, 66% in frog and 53% in various fishes UII. No appreciable homology is seen with other peptides. Antibody crossreactivity in various species is not established.
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Affinity Purified
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, 0.02% sodium merthiolate, 40% glycerol.
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, 0.02% sodium merthiolate, 40% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
389
Applicable Applications for anti-GPR14 antibody
ELISA
Application Notes
Suitable for use in ELISA. Other applications not tested.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide/well.
Optimal dilutions to be determined by the researcher.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide/well.
Optimal dilutions to be determined by the researcher.
Immunogen
An 18-aa peptide near the C-terminus of rat GPR14 (2) was synthesized,.coupled to KLH (carrier protein)
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-GPR14 antibody
Urotensins are neuropeptide secreted from the urophysis in the caudal neurosecretory system of the fishes. Two bioactive Urotensins, U1 and UII have been cloned from various species including mammals. UI is 41 aa peptide, which showed prolonged hypotensive effects in mammals. It is structurally similar to mammalian corticotropin-releasing factor. UII is a vasoactive \'somatostatin-like" 12-aa cyclic peptide with similarity to somatostatin-14. Human UII is composed of only 11 aa residues, while fish and frog UII possess 12 and 13 aa, respectively. The cyclic region of the UII, which is responsible for the biological activity of the peptide, has been fully conserved from fish to human. UII expression has been observed predominantly in the spinal cord.
Product Categories/Family for anti-GPR14 antibody
References
• 1. Coulouran Y et al (1999) FEBS Lett. 457, 28-32; Coulouran Y et al (1999) Proc. Natl. Acad. Sci. 95, 15803-158082. Ames RS et al (1999) Nature 401, 282-286; Marchese A et al (1995) Genomics 29, 335-344; Tal M et al (1995) BBRC 209, 752-759
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
42,130 Da
NCBI Official Full Name
G-protein coupled receptor 14
NCBI Official Synonym Full Names
urotensin 2 receptor
NCBI Official Symbol
UTS2R
NCBI Official Synonym Symbols
UTR; UTR2; GPR14; UR-2-R
NCBI Protein Information
urotensin-2 receptor; UR-II-R; urotensin II receptor; G protein-coupled receptor 14; G-protein coupled receptor 14
UniProt Protein Name
Urotensin-2 receptor
UniProt Gene Name
UTS2R
UniProt Synonym Gene Names
GPR14
UniProt Entry Name
UR2R_HUMAN
Similar Products
Product Notes
The GPR14 uts2r (Catalog #AAA621738) is an Antibody produced from Host: Rabbit Source: Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti - GPR14 (UII Receptor) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPR14 can be used in a range of immunoassay formats including, but not limited to, ELISA. Suitable for use in ELISA. Other applications not tested. Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide/well. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the GPR14 uts2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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