Western Blot (WB)
(GPM6A Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GPM6A antibody detected the GPM6A protein (arrow).)
Rabbit GPM6A Polyclonal Antibody | anti-GPM6A antibody
GPM6A Antibody (C-term)
Western Blot (WB)
(GPM6A Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GPM6A antibody detected the GPM6A protein (arrow).)
Western Blot (WB)
(GPM6A Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GPM6A antibody detected the GPM6A protein (arrow).)
Immunohistochemistry (IHC)
(GPM6A Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GPM6A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(GPM6A Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GPM6A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Michibata, H., et al. Stem Cells Dev. 18(4):629-639(2009)
Boks, M.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (6), 707-711 (2008) :
Liang, Y.J., et al. Cell Res. 18(7):768-779(2008)
NCBI and Uniprot Product Information
Uniprot Description
GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family.
Protein type: Channel, calcium; Cell surface; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 4q34
Cellular Component: neuron projection; cell soma; integral to membrane; plasma membrane; dendritic spine; vesicle; filopodium
Molecular Function: protein binding; calcium channel activity
Biological Process: positive regulation of filopodium formation; synaptogenesis; neuron migration; stem cell differentiation; neurite morphogenesis
Research Articles on GPM6A
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Product Notes
The GPM6A gpm6a (Catalog #AAA9213683) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 246-275. The GPM6A Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's GPM6A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the GPM6A gpm6a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPM6A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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