Immunohistochemistry (IHC)
(Anti-GPC4 / Glypican 4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit GPC4 / Glypican 4 Polyclonal Antibody | anti-GPC4 antibody
Rabbit Polyclonal to Human GPC4 / Glypican 4
Predicted Reactivity: Mouse, Rat, Dog (at least 90% immunogen sequence identity)
Predicted Reactivity: Mouse, Rat, Dog (at least 90% immunogen sequence identity)
Immunohistochemistry (IHC)
(Anti-GPC4 / Glypican 4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GPC4 / Glypican 4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GPC4 / Glypican 4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GPC4 / Glypican 4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
NCBI and Uniprot Product Information
NCBI Description
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]
Uniprot Description
GPC4: Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system. Belongs to the glypican family.
Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: Xq26.1
Cellular Component: lysosomal lumen; proteinaceous extracellular matrix; extracellular space; Golgi lumen; integral to plasma membrane; plasma membrane; nucleus; external side of plasma membrane
Molecular Function: heparan sulfate proteoglycan binding
Biological Process: chondroitin sulfate metabolic process; cell proliferation; glycosaminoglycan biosynthetic process; phototransduction, visible light; glycosaminoglycan catabolic process; anatomical structure morphogenesis; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis; retinoid metabolic process
Disease: Simpson-golabi-behmel Syndrome, Type 1; Wilms Tumor 1
Research Articles on GPC4
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Product Notes
The GPC4 gpc4 (Catalog #AAA247849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GPC4 / Glypican 4 reacts with Gorilla, Human, Monkey, Rabbit Predicted Reactivity: Mouse, Rat, Dog (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's GPC4 / Glypican 4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 - 12.5 ug/ml). Researchers should empirically determine the suitability of the GPC4 gpc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPC4 / Glypican 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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