Rabbit anti-Human GPATCH4 Polyclonal Antibody | anti-GPATCH4 antibody

GPATCH4, ID (GPATCH4, GPATC4, G patch domain-containing protein 4) (Biotin)

Cat. Num. AAA6303438

• Gene Names: GPATCH4; GPATC4
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GPATCH4; Polyclonal Antibody; ID (GPATCH4; GPATC4; G patch domain-containing protein 4) (Biotin); G patch domain-containing protein 4; anti-GPATCH4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-GPATCH4 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GPATCH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-262 amino acids from the Central region of human GPATCH4.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(GPATCH4 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GPATCH4 antibody detected the GPATCH4 protein (arrow).)

Related Product Information for anti-GPATCH4 antibody

GPATCH4 (G patch domain-containing protein 4) is a 446 amino acid protein containing one G-patch domain. Existing as three alternatively spliced isoforms, the gene encoding GPATCH4 maps to human chromosome 1q23.1 and mouse chromosome 3 F1. Spanning around 260 million base pairs, chromosome 1 is the largest human chromosome and comprises 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Product Categories/Family for anti-GPATCH4 antibody

Antibodies; Disease Markers

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Olsen, J.V., et al. Cell 127(3):635-648(2006). Andersen, J.S., et al. Nature 433(7021):77-83(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 33356552
• NCBI GeneID: 54865
• NCBI Accession #: NP_056405.2
• NCBI GenBank Nucleotide #: NM_015590.3
• UniProt Accession #: Q5T3I0; Q5T3I1; Q6ZUE7; Q8IWG8; Q9NXH4
• Molecular Weight: 50,381 Da
• NCBI Official Full Name: G patch domain-containing protein 4 isoform 1
• NCBI Official Synonym Full Names: G patch domain containing 4
• NCBI Official Symbol: GPATCH4
• NCBI Official Synonym Symbols: GPATC4
• NCBI Protein Information: G patch domain-containing protein 4
• UniProt Protein Name: G patch domain-containing protein 4
• Protein Family: G patch domain-containing protein
• UniProt Gene Name: GPATCH4
• UniProt Synonym Gene Names: GPATC4
• UniProt Entry Name: GPTC4_HUMAN