Western Blot
(Western Blot analysis of HepG2 cells, using GPAA1 Polyclonal Antibody at dilution of 1:200.)
Rabbit GPAA1 Polyclonal Antibody | anti-GPAA1 antibody
GPAA1 Antibody
IHC: 1:50-1:200
Western Blot
(Western Blot analysis of HepG2 cells, using GPAA1 Polyclonal Antibody at dilution of 1:200.)
Western Blot
(Western Blot analysis of HepG2 cells, using GPAA1 Polyclonal Antibody at dilution of 1:200.)
NCBI and Uniprot Product Information
Observed MW 60~68 kDa
NCBI Description
Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq, Jul 2008]
Uniprot Description
GPAA1: Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Endoplasmic reticulum; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: endoplasmic reticulum membrane; membrane; GPI-anchor transamidase complex
Molecular Function: tubulin binding; protein binding; GPI-anchor transamidase activity
Biological Process: cellular protein metabolic process; attachment of GPI anchor to protein; C-terminal protein lipidation; protein complex assembly; post-translational protein modification; protein retention in ER
Research Articles on GPAA1
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Product Notes
The GPAA1 gpaa1 (Catalog #AAA2519355) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPAA1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPAA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:1000 IHC: 1:50-1:200 . Researchers should empirically determine the suitability of the GPAA1 gpaa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPAA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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