Rabbit anti-Mouse, Rat GNG7 Polyclonal Antibody | anti-GNG7 antibody

GNG7 Polyclonal Antibody

Cat. Num. AAA3008372

• Reactivity: Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: GNG7; Polyclonal Antibody; GNG7 Polyclonal Antibody; GNGT7; anti-GNG7 antibody

• Host: Rabbit
• Reactivity: Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: GNG7 polyclonal antibody detects endogenous levels of GNG7 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 68

• Applicable Applications for anti-GNG7 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Recombinant protein of human GNG7.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using GNG7 antibody.)

Related Product Information for anti-GNG7 antibody

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.

NCBI and Uniprot Product Information

• NCBI GI #: 32698769
• NCBI GeneID: 2788
• NCBI Accession #: NP_443079.1
• NCBI GenBank Nucleotide #: NP_443079.1
• UniProt Accession #: O60262
• Molecular Weight: ~ 12kDa
• NCBI Official Full Name: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
• NCBI Official Synonym Full Names: G protein subunit gamma 7
• NCBI Official Symbol: GNG7
• NCBI Protein Information: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
• UniProt Protein Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
• UniProt Gene Name: GNG7
• UniProt Synonym Gene Names: GNGT7
• UniProt Entry Name: GBG7_HUMAN

Uniprot Description

G-gamma 7: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. Belongs to the G protein gamma family.

Protein type: G protein, heterotrimeric gamma; G protein; G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: plasma membrane; heterotrimeric G-protein complex

Molecular Function: signal transducer activity

Biological Process: regulation of adenylate cyclase activity; G-protein coupled receptor protein signaling pathway; synaptic transmission; behavioral fear response; receptor guanylyl cyclase signaling pathway; energy reserve metabolic process; locomotory behavior; regulation of G-protein coupled receptor protein signaling pathway