Rabbit GNB5 Polyclonal Antibody | anti-GNB5 antibody

GNB5 Rabbit Polyclonal

Cat. Num. AAA769775

• Gene Names: GNB5; GB5
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: GNB5; Polyclonal Antibody; GNB5 Rabbit Polyclonal; anti-GNB5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 126

• Applicable Applications for anti-GNB5 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: Guanine nucleotide binding protein (G protein), beta 5
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human ovary tumor using MBS769775 (GNB5 antibody) at dilution of 1:100)

Western Blot (WB)

(mouse brain tissue were subjected to SDS PAGE followed by western blot with MBS769775 (GNB5 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 15079705
• NCBI GeneID: 10681
• Molecular Weight: 31,247 Da
• NCBI Official Full Name: GNB5 protein
• NCBI Official Synonym Full Names: G protein subunit beta 5
• NCBI Official Symbol: GNB5
• NCBI Official Synonym Symbols: GB5
• NCBI Protein Information: guanine nucleotide-binding protein subunit beta-5
• UniProt Protein Name: Guanine nucleotide-binding protein subunit beta-5
• Protein Family: Guanine nucleotide-binding protein
• UniProt Gene Name: GNB5
• UniProt Entry Name: GBB5_HUMAN

NCBI Description

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]

Uniprot Description

G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, heterotrimeric beta

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: cytosol; myelin sheath; nucleus; photoreceptor inner segment; photoreceptor outer segment; plasma membrane

Molecular Function: chaperone binding; G-protein gamma-subunit binding; GTPase activator activity; GTPase activity; protein binding; signal transducer activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity; protein folding; signal transduction