Rabbit anti-Human, Mouse GNB2 Polyclonal Antibody | anti-GNB2 antibody

GNB2 Antibody

Cat. Num. AAA7046560

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: GNB2; Polyclonal Antibody; GNB2 Antibody; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; G protein subunit beta-2; Transducin beta chain 2; anti-GNB2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 340

• Applicable Applications for anti-GNB2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Species: Human
• Immunogen: Recombinant human Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-2 protein (1-340AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-25017 / sc-25018 / sc-380
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: GNB2 antibody at 2.22 ug/mlLane 1: Mouse liver tissueLane 2: Mouse lung tissueLane 3: NIH/3T3 whole cell lysateLane 4: Jurkat whole cell lysateLane 5: 293T whole cell lysateLane 6: Hela whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 38,26 kDaObserved band size: 37,45 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7046560 at dilution of 1:100)

Related Product Information for anti-GNB2 antibody

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

NCBI and Uniprot Product Information

• NCBI GI #: 20357529
• NCBI GeneID: 2783
• NCBI Accession #: NP_005264.2
• NCBI GenBank Nucleotide #: NM_005273.3
• UniProt Accession #: P62879; P11016; P54312; B3KPU1
• Molecular Weight: 25,931 Da
• NCBI Official Full Name: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
• NCBI Official Synonym Full Names: G protein subunit beta 2
• NCBI Official Symbol: GNB2
• NCBI Protein Information: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
• UniProt Protein Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
• UniProt Gene Name: GNB2
• UniProt Entry Name: GBB2_HUMAN

NCBI Description

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. [provided by RefSeq, Jul 2008]

Uniprot Description

G-beta 2: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family.

Protein type: G protein, heterotrimeric beta; G protein; G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 7q22

Cellular Component: cytosol; extracellular space; focal adhesion; lysosomal membrane; membrane; perinuclear region of cytoplasm; plasma membrane; vesicle

Molecular Function: GTPase activity; GTPase binding; protein binding; protein complex binding

Biological Process: G-protein coupled receptor protein signaling pathway; protein folding