Western Blot (WB)
(WB Suggested Anti-GMPR2 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate)
Rabbit GMPR2 Polyclonal Antibody | anti-GMPR2 antibody
GMPR2 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-GMPR2 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate)
Western Blot (WB)
(WB Suggested Anti-GMPR2 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate)
Target Description: GMPR2 catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. It plays a role in modulating cellular differentiation.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of guanosine monophosphate (GMP) to inosine monophosphate (IMP). The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
Uniprot Description
GMPR2: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. Belongs to the IMPDH/GMPR family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.7.1.7; Nucleotide Metabolism - purine; Oxidoreductase
Chromosomal Location of Human Ortholog: 14q12
Cellular Component: cytosol
Molecular Function: GMP reductase activity; metal ion binding
Biological Process: nucleobase, nucleoside and nucleotide metabolic process; purine salvage; GMP metabolic process; purine base metabolic process
Research Articles on GMPR2
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Product Notes
The GMPR2 gmpr2 (Catalog #AAA3208985) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GMPR2 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's GMPR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the GMPR2 gmpr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GAGADFVMLG GMLAGHSESG GELIERDGKK YKLFYGMSSE MAMKKYAGGV. It is sometimes possible for the material contained within the vial of "GMPR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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