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Western Blot (WB) (All lanes: Glycogen phosphorylase, liver form antibody at 2ug/ml)

Rabbit anti-Human Glycogen phosphorylase Polyclonal Antibody | anti-PYGL antibody

Glycogen phosphorylase, liver form Polyclonal Antibody

Gene Names
PYGL; GSD6
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Glycogen phosphorylase; Polyclonal Antibody; liver form Polyclonal Antibody; PYGL; anti-PYGL antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Glycogen phosphorylase, liver form polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
813
Applicable Applications for anti-PYGL antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Glycogen phosphorylase, liver form protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(All lanes: Glycogen phosphorylase, liver form antibody at 2ug/ml)

Western Blot (WB) (All lanes: Glycogen phosphorylase, liver form antibody at 2ug/ml)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human placenta using at dilution of 1:20.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human placenta using at dilution of 1:20.)
Related Product Information for anti-PYGL antibody
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.However, all known phosphorylases share catalytic and structural properties.
Product Categories/Family for anti-PYGL antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
93,134 Da
NCBI Official Full Name
glycogen phosphorylase, liver form isoform 2
NCBI Official Synonym Full Names
phosphorylase, glycogen, liver
NCBI Official Symbol
PYGL
NCBI Official Synonym Symbols
GSD6
NCBI Protein Information
glycogen phosphorylase, liver form
UniProt Protein Name
Glycogen phosphorylase, liver form
Protein Family
UniProt Gene Name
PYGL
UniProt Entry Name
PYGL_HUMAN

Uniprot Description

PYGL: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Defects in PYGL are the cause of glycogen storage disease type 6 (GSD6). A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected. Belongs to the glycogen phosphorylase family.

Protein type: Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.1; Transferase

Chromosomal Location of Human Ortholog: 14q21-q22

Cellular Component: cytoplasm; cytosol; plasma membrane

Molecular Function: AMP binding; ATP binding; bile acid binding; drug binding; glycogen phosphorylase activity; protein binding; purine binding; pyridoxal phosphate binding; vitamin binding

Biological Process: glucose homeostasis; glycogen catabolic process; glycogen metabolic process

Disease: Glycogen Storage Disease Vi

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Product Notes

The PYGL pygl (Catalog #AAA9415694) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glycogen phosphorylase, liver form Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Glycogen phosphorylase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the PYGL pygl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glycogen phosphorylase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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