Rabbit anti-Rat Glutamate Transporter EAAT2 Polyclonal Antibody | anti-GLT1 antibody
Glutamate Transporter EAAT2 (GLT1)
Gene Names
GLT1; EAAT2
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Glutamate Transporter EAAT2; Polyclonal Antibody; Glutamate Transporter EAAT2 (GLT1); Anti -Glutamate Transporter EAAT2 (GLT1); anti-GLT1 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat Glutamate Transporter. Has no significant sequence homology to other glutamate transporters.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.1% BSA.
Applicable Applications for anti-GLT1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique.
ELISA: 0.5-1ug/ml
Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique.
ELISA: 0.5-1ug/ml
Immunogen
A 16 AA synthetic peptide from the cytoplasmic, N-terminus of rat GLT1 (KLH coupled)
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-GLT1 antibody
Glutamate is the main excitatory neurotransmitter in the brain. To date five glutamate Transporters have been cloned: GLAST (EAAT1), GLT1 (EAAT2), EAAC1 (EAAT3), EAAT4, and EAAT5. These transporters are believed to be critical in reducing potentially toxic extracellular concentration of glutamate by rapid uptake into nerve terminals and glial cells. Glutamate transporters (525-573 AA) display about 55% homology and are predicted to contain up to 6-10 transmembrane domains. Immunolocalization studies indicate that GLT1 is localized in astroglial cells throughout the brain and spinal cord. EAAC1 is specific for certain neurons and purkinje cells, and specifically enriched in cortex, hippocampus, and caudate-putamen and confined to presynaptic and postsynaptic elements. GLAST has been observed in both neuron and astroglia. It is most abundant in Bergmann glia, cortex, hippocampus and cerebellum. EAAT4 has properties of ligand gated Cl-channel. It is localized mainly in cerebellar Purkinje cells in rat and human CNS.
Product Categories/Family for anti-GLT1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
glutamate transporter GLT1
NCBI Official Symbol
GLT1
NCBI Official Synonym Symbols
EAAT2
NCBI Protein Information
glutamate transporter GLT1
Protein Family
Similar Products
Product Notes
The GLT1 (Catalog #AAA613323) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glutamate Transporter EAAT2 (GLT1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Glutamate Transporter EAAT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique. ELISA: 0.5-1ug/ml. Researchers should empirically determine the suitability of the GLT1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutamate Transporter EAAT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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