Western Blot (WB)
(Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue with Glutamate Receptor 1 Rabbit pAb EA265 diluted at 1:2,000.)
Rabbit Glutamate Receptor 1 Polyclonal Antibody | anti-GRIA1 antibody
Glutamate Receptor 1 Rabbit pAb
Western Blot (WB)
(Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue with Glutamate Receptor 1 Rabbit pAb EA265 diluted at 1:2,000.)
Western Blot (WB)
(Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue with Glutamate Receptor 1 Rabbit pAb EA265 diluted at 1:2,000.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using Glutamate Receptor 1(EA265)Rabbit pAb diluted at 1:200.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using Glutamate Receptor 1(EA265)Rabbit pAb diluted at 1:200.)
NCBI and Uniprot Product Information
NCBI Description
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
GluR1: an integral membrane protein belonging to the glutamate-gated ion channel family. L-glutamate (Glu) acts as an excitatory neurotransmitter at many synapses in the central nervous system. Glutamate receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Each of the four GluR proteins (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. Expressed in granule and pyramidal cells in the hippocampal formation.
Protein type: Membrane protein, integral; Channel, ligand-gated; Channel, calcium; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: postsynaptic membrane; synaptic vesicle; endoplasmic reticulum membrane; recycling endosome; cell surface; cell soma; postsynaptic density; dendrite; dendritic spine; plasma membrane; cell junction
Molecular Function: protein binding; extracellular-glutamate-gated ion channel activity; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; glutamate receptor activity; PDZ domain binding
Biological Process: synaptic transmission, glutamatergic; synaptic transmission; long-term memory; ionotropic glutamate receptor signaling pathway; receptor internalization; signal transduction
Research Articles on GRIA1
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Product Notes
The GRIA1 gria1 (Catalog #AAA8808375) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glutamate Receptor 1 Rabbit pAb reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Glutamate Receptor 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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