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Western Blot (WB) (Western blot analysis of GLIPR1L2 in human testis tissue lysate with GLIPR1L2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Rabbit anti-Human GLIPR1L2 Polyclonal Antibody | anti-GLIPR1L2 antibody

GLIPR1L2 Antibody

Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
GLIPR1L2 antibody is affinity chromatography purified via peptide column.
Synonyms
GLIPR1L2; Polyclonal Antibody; GLIPR1L2 Antibody; GLIPR1-like protein 2; GLI pathogenesis-related 1 like 2; anti-GLIPR1L2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
GLIPR1L2 antibody is human specific. At least two isoforms of GLIPR1L2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.
Purity/Purification
GLIPR1L2 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
344
Applicable Applications for anti-GLIPR1L2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
GLIPR1L2 antibody can be used for detection of GLIPR1L2 by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
GLIPR1L2 antibody was raised against an 15 amino acid peptide near the center of human GLIPR1L2.
Buffer
GLIPR1L2 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
GLIPR1L2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Western Blot (WB)

(Western blot analysis of GLIPR1L2 in human testis tissue lysate with GLIPR1L2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of GLIPR1L2 in human testis tissue lysate with GLIPR1L2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Immunohistochemistry (IHC)

(Immunohistochemistry of GLIPR1L2 in human testis tissue with GLIPR1L2 antibody at 5 μg/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of GLIPR1L2 in human testis tissue with GLIPR1L2 antibody at 5 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of GLIPR1L2 in human testis tissue with GLIPR1L2 antibody at 20 μg/mL.)

Immunofluorescence (IF) (Immunofluorescence of GLIPR1L2 in human testis tissue with GLIPR1L2 antibody at 20 μg/mL.)
Related Product Information for anti-GLIPR1L2 antibody
The GLIPR1-like 2 protein (GLIPR1L2) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (2). GLIPR1L2 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3). Deletions of the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster have been observed in some multiple myeloma samples, suggesting that these proteins may also be involved in the pathogenesis of multiple myeloma (4).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 28; 31; 38 kDa

Observed: 28 kDa
NCBI Official Full Name
GLIPR1-like protein 2 isoform 1
NCBI Official Synonym Full Names
GLI pathogenesis-related 1 like 2
NCBI Official Symbol
GLIPR1L2
NCBI Protein Information
GLIPR1-like protein 2
UniProt Protein Name
GLIPR1-like protein 2
Protein Family
UniProt Gene Name
GLIPR1L2
UniProt Entry Name
GRPL2_HUMAN

NCBI Description

This gene encodes a member of the cysteine-rich secretory protein, antigen 5, and pathogenesis-related 1 superfamily. Members of this family have roles in a variety of processes, including cancer and immune defense. This gene is located in a cluster with two related genes on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

GLIPR1L2: a member of the cysteine-rich secretory protein, antigen 5, and pathogenesis-related 1 superfamily. Members of this family have roles in a variety of processes, including cancer and immune defense. This gene is located in a cluster with two related genes on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q21.2

Cellular Component: integral to membrane

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Product Notes

The GLIPR1L2 glipr1l2 (Catalog #AAA153377) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GLIPR1L2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GLIPR1L2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). GLIPR1L2 antibody can be used for detection of GLIPR1L2 by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the GLIPR1L2 glipr1l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLIPR1L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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