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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using MBS7051989 at dilution of 1:100)

Rabbit anti-Human GJC1 Polyclonal Antibody | anti-GJC1 antibody

GJC1 Antibody

Gene Names
GJC1; CX45; GJA7
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
GJC1; Polyclonal Antibody; GJC1 Antibody; Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein; GJA7; anti-GJC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
396
Applicable Applications for anti-GJC1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:20-1:200
IF: 1:50-1:200
Immunogen
Recombinant Human Gap junction gamma-1 protein (247-396AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7051989 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using MBS7051989 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7051989 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver tissue using MBS7051989 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of A549 cells using MBS7051989 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of A549 cells using MBS7051989 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Western Blot (WB)

(Western BlotPositive WB detected in: A549 whole cell lysateAll lanes: GJC1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 46 KDaObserved band size: 46 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: A549 whole cell lysateAll lanes: GJC1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 46 KDaObserved band size: 46 KDa)
Related Product Information for anti-GJC1 antibody
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,470 Da
NCBI Official Full Name
gap junction gamma-1 protein
NCBI Official Synonym Full Names
gap junction protein gamma 1
NCBI Official Symbol
GJC1
NCBI Official Synonym Symbols
CX45; GJA7
NCBI Protein Information
gap junction gamma-1 protein
UniProt Protein Name
Gap junction gamma-1 protein
UniProt Gene Name
GJC1
UniProt Synonym Gene Names
GJA7; Cx45

NCBI Description

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

GJC1: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.

Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: connexon complex; endoplasmic reticulum membrane; gap junction; plasma membrane

Biological Process: gap junction assembly; intercellular junction assembly; muscle contraction

Research Articles on GJC1

Similar Products

Product Notes

The GJC1 gjc1 (Catalog #AAA7051989) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GJC1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GJC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the GJC1 gjc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GJC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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