Western Blot (WB)
(Western blot analysis of GINS1 Antibody (N-term) in MCF-7 cell line lysates (35ug/lane). GINS1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human GINS1 Polyclonal Antibody | anti-GINS1 antibody
GINS1, NT (GINS1, KIAA0186, PSF1, DNA replication complex GINS protein PSF1, GINS complex subunit 1) (AP)
Gene Names
GINS1; PSF1; RP4-691N24.2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
GINS1; Polyclonal Antibody; NT (GINS1; KIAA0186; PSF1; DNA replication complex GINS protein PSF1; GINS complex subunit 1) (AP); GINS complex subunit 1; anti-GINS1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-GINS1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
GINS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2~32 amino acids from the N-terminal region of human GINS1.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western blot analysis of GINS1 Antibody (N-term) in MCF-7 cell line lysates (35ug/lane). GINS1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of GINS1 Antibody (N-term) in MCF-7 cell line lysates (35ug/lane). GINS1 (arrow) was detected using the purified Pab.)
Related Product Information for anti-GINS1 antibody
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).
Product Categories/Family for anti-GINS1 antibody
References
Nagahama, Y., et al. Cancer Res. 70(3):1215-1224(2010). Kamada, K., et al. Nat. Struct. Mol. Biol. 14(5):388-396(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,988 Da
NCBI Official Full Name
GINS1 protein
NCBI Official Synonym Full Names
GINS complex subunit 1 (Psf1 homolog)
NCBI Official Symbol
GINS1
NCBI Official Synonym Symbols
PSF1; RP4-691N24.2
NCBI Protein Information
DNA replication complex GINS protein PSF1; partner of sld five-1
UniProt Protein Name
DNA replication complex GINS protein PSF1
Protein Family
UniProt Gene Name
GINS1
UniProt Synonym Gene Names
KIAA0186; PSF1
UniProt Entry Name
PSF1_HUMAN
NCBI Description
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).[supplied by OMIM, Mar 2008]
Uniprot Description
GINS1: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. GINS1 is essential for function. Belongs to the GINS1/PSF1 family.
Protein type: DNA replication; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component: nucleoplasm; cytoplasm; nucleus
Biological Process: DNA strand elongation during DNA replication; mitotic cell cycle; inner cell mass cell proliferation
Research Articles on GINS1
Similar Products
Product Notes
The GINS1 gins1 (Catalog #AAA6302259) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GINS1, NT (GINS1, KIAA0186, PSF1, DNA replication complex GINS protein PSF1, GINS complex subunit 1) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GINS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the GINS1 gins1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GINS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
