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Western Blot (WB) (GGT7 Antibody (N-term) western blot analysis in uterus tumor cell line lysates (35ug/lane).This demonstrates the GGT7 antibody detected the GGT7 protein (arrow).)

Rabbit anti-Human GGT7 Polyclonal Antibody | anti-GGT7 antibody

GGT7, NT (GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7, Gamma-glutamyltransferase 7 heavy chain, Gamma-glutamyltransferase 7 li

Gene Names
GGT7; GGT4; GGTL3; GGTL5; D20S101; dJ18C9.2
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
GGT7; Polyclonal Antibody; NT (GGT7; GGTL3; GGTL5; Gamma-glutamyltransferase 7; Gamma-glutamyltransferase-like 3; Gamma-glutamyltransferase-like 5; Gamma-glutamyltranspeptidase 7; Glutathione hydrolase 7; Gamma-glutamyltransferase 7 heavy chain; Gamma-glutamyltransferase 7 li; Gamma-glutamyltransferase 7 light chain; anti-GGT7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-GGT7 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
GGT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of human GGT7.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GGT7 Antibody (N-term) western blot analysis in uterus tumor cell line lysates (35ug/lane).This demonstrates the GGT7 antibody detected the GGT7 protein (arrow).)

Western Blot (WB) (GGT7 Antibody (N-term) western blot analysis in uterus tumor cell line lysates (35ug/lane).This demonstrates the GGT7 antibody detected the GGT7 protein (arrow).)

Immunohistochemistry (IHC)

(GGT7 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GGT7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (GGT7 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GGT7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-GGT7 antibody
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis.
Product Categories/Family for anti-GGT7 antibody
References
Rose, J. Phd, et al. Mol. Med. (2010). In press: Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008). He, X., et al. Biochem. Biophys. Res. Commun. 297(3):528-536(2002). Figlewicz, D.A., et al. Genomics 17(2):299-305(1993).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70,467 Da
NCBI Official Full Name
gamma-glutamyltransferase 7
NCBI Official Synonym Full Names
gamma-glutamyltransferase 7
NCBI Official Symbol
GGT7
NCBI Official Synonym Symbols
GGT4; GGTL3; GGTL5; D20S101; dJ18C9.2
NCBI Protein Information
gamma-glutamyltransferase 7; GGT 7; glutathione hydrolase 7; gamma-glutamyltransferase 4; gamma-glutamyltranspeptidase 7; gamma-glutamyltransferase-like 3; gamma-glutamyltransferase-like 5; gamma-glutamyltranspeptidase-like 3
UniProt Protein Name
Gamma-glutamyltransferase 7
Protein Family
UniProt Gene Name
GGT7
UniProt Synonym Gene Names
GGTL3; GGTL5; GGT 7
UniProt Entry Name
GGT7_HUMAN

NCBI Description

This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008]

Uniprot Description

GGTL3: Cleaves glutathione conjugates. Belongs to the gamma-glutamyltransferase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Other Amino Acids Metabolism - glutathione; EC 3.4.19.13; Other Amino Acids Metabolism - selenoamino acid; Transferase; Other Amino Acids Metabolism - cyanoamino acid; Lipid Metabolism - arachidonic acid; EC 2.3.2.2; Membrane protein, integral; Other Amino Acids Metabolism - taurine and hypotaurine

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: anchored to external side of plasma membrane; integral to membrane

Molecular Function: gamma-glutamyltransferase activity

Biological Process: leukotriene biosynthetic process; glutathione metabolic process; glutathione biosynthetic process; proteolysis

Research Articles on GGT7

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Product Notes

The GGT7 ggt7 (Catalog #AAA6302171) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GGT7, NT (GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7, Gamma-glutamyltransferase 7 heavy chain, Gamma-glutamyltransferase 7 li reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GGT7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:10-50 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the GGT7 ggt7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GGT7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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