Rabbit GEFT Polyclonal Antibody | anti-GEFT antibody
GEFT
Gene Names
ARHGEF25; GEFT; p63RhoGEF
Reactivity
HumanPredicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
GEFT; Polyclonal Antibody; Purified Rabbit Anti Human GEFT Polyclonal antibody; ARHGEF25; p63RhoGEF; anti-GEFT antibody
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2166
Applicable Applications for anti-GEFT antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
IHC: 1:100-500
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 51aa-325aa of human GEFT.
Cellular Localization
Cell Membrane, Cytoplasm and Membrane
Related Product Information for anti-GEFT antibody
Homo sapiens RhoA/RAC/CDC42 exchange factor, mRNA
References
Souchet M, Portales-Casamar E, Mazurais D. et al. Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere. Journal of cell science. 115(3):629-640 (2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
55KD
NCBI Official Full Name
Homo sapiens RhoA/RAC/CDC42 exchange factor, mRNA
NCBI Official Synonym Full Names
Rho guanine nucleotide exchange factor 25
NCBI Official Symbol
ARHGEF25
NCBI Official Synonym Symbols
GEFT; p63RhoGEF
NCBI Protein Information
rho guanine nucleotide exchange factor 25
NCBI Description
Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Research Articles on GEFT
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Product Notes
The GEFT (Catalog #AAA8562941) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GEFT reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GEFT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20000-80000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the GEFT for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GEFT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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