Rabbit GDI1 Polyclonal Antibody | anti-GDI1 antibody

GDI1 Rabbit Polyclonal

Cat. Num. AAA769636

• Gene Names: GDI1; 1A; GDIL; MRX41; MRX48; OPHN2; XAP-4; RABGD1A; RABGDIA
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry, Western Blot, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: GDI1; Polyclonal Antibody; GDI1 Rabbit Polyclonal; anti-GDI1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 447

• Applicable Applications for anti-GDI1 antibody: ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP)
• Immunogen: GDP dissociation inhibitor 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human breast cancer using MBS769636 (GDI1 antibody) at dilution of 1:50)

Western Blot (WB)

(mouse brain tissue were subjected to SDS PAGE followed by western blot with MBS769636 (GDI1 Antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 49457546
• NCBI GeneID: 2664
• UniProt Accession #: P31150; P50394; Q6FG50; Q7Z2G6; Q7Z2G9; Q7Z2H5; Q7Z2I6
• Molecular Weight: 50,583 Da
• NCBI Official Full Name: GDI1, partial
• NCBI Official Synonym Full Names: GDP dissociation inhibitor 1
• NCBI Official Symbol: GDI1
• NCBI Official Synonym Symbols: 1A; GDIL; MRX41; MRX48; OPHN2; XAP-4; RABGD1A; RABGDIA
• NCBI Protein Information: rab GDP dissociation inhibitor alpha
• UniProt Protein Name: Rab GDP dissociation inhibitor alpha
• Protein Family: Guanosine nucleotide diphosphate dissociation inhibitor
• UniProt Gene Name: GDI1
• UniProt Synonym Gene Names: GDIL; OPHN2; RABGDIA; XAP4; Rab GDI alpha; GDI-1
• UniProt Entry Name: GDIA_HUMAN

NCBI Description

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008]

Uniprot Description

GDI1: a GDP dissociation inhibitor protein expressed primarily in neural and sensory tissues. GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the Rab family, small GTP-binding proteins of the Ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from Rab proteins and release GDP from membrane-bound Rabs. Mutations have been linked to X-linked nonspecific mental retardation.

Protein type: Motility/polarity/chemotaxis; G protein regulator, misc.

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; cytosol; Golgi apparatus; midbody; myelin sheath; neuron projection; protein complex

Molecular Function: GDP-dissociation inhibitor activity; GTPase activator activity; oxidoreductase activity; protein binding; Rab GDP-dissociation inhibitor activity; Rab GTPase binding

Biological Process: negative regulation of axonogenesis; positive regulation of GTPase activity; protein transport; Rab protein signal transduction; regulation of small GTPase mediated signal transduction; response to calcium ion; signal transduction

Disease: Mental Retardation, X-linked 41