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Western Blot (WB) (Gel: 8+15%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse pancreas tissue, human fetal brain tissue, Primary antibody: 121717(GDPD5 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Rabbit anti-Human, Mouse GDE2 Polyclonal Antibody | anti-GDE2 antibody

GDE2 Rabbit pAb

Gene Names
GDPD5; GDE2; PP1665
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity purified
Synonyms
GDE2; Polyclonal Antibody; GDE2 Rabbit pAb; PP1665; anti-GDE2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-GDE2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Fusion protein of human GDPD5
Conjugation
Unconjugated
Molecular Function
Glycerophosphodiester phosphodiesterases, such as GDPD5, are involved in glycerol metabolism. Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
Modification
Unmodified
Cell Position
Cell projection, Cytoplasm, Membrane
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8+15%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse pancreas tissue, human fetal brain tissue, Primary antibody: 121717(GDPD5 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Western Blot (WB) (Gel: 8+15%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse pancreas tissue, human fetal brain tissue, Primary antibody: 121717(GDPD5 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)
Product Categories/Family for anti-GDE2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
40,577 Da
NCBI Official Full Name
Homo sapiens glycerophosphodiester phosphodiesterase domain containing 5, mRNA
NCBI Official Synonym Full Names
glycerophosphodiester phosphodiesterase domain containing 5
NCBI Official Symbol
GDPD5
NCBI Official Synonym Symbols
GDE2; PP1665
NCBI Protein Information
glycerophosphodiester phosphodiesterase domain-containing protein 5
UniProt Protein Name
Glycerophosphodiester phosphodiesterase domain-containing protein 5
UniProt Gene Name
GDPD5
UniProt Synonym Gene Names
GDE2
UniProt Entry Name
GDPD5_HUMAN

NCBI Description

Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]

Uniprot Description

GDPD5: Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine. Belongs to the glycerophosphoryl diester phosphodiesterase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; EC 3.1.-.-; Membrane protein, integral; Phosphodiesterase

Chromosomal Location of Human Ortholog: 11q13.4-q13.5

Cellular Component: growth cone; perinuclear region of cytoplasm; integral to membrane; endomembrane system

Molecular Function: glycerophosphodiester phosphodiesterase activity

Biological Process: glycerol metabolic process; negative regulation of Notch signaling pathway; lipid metabolic process; spinal cord motor neuron differentiation; positive regulation of neuron differentiation; regulation of timing of cell differentiation; neurite development; cerebral cortex neuron differentiation

Research Articles on GDE2

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Product Notes

The GDE2 gdpd5 (Catalog #AAA4754368) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GDE2 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GDE2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GDE2 gdpd5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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