Rabbit GAS8 Polyclonal Antibody | anti-GAS8 antibody

GAS8 Antibody

Cat. Num. AAA9401696

• Gene Names: GAS8; GAS11
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: GAS8; Polyclonal Antibody; GAS8 Antibody; GAS11; anti-GAS8 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total GAS8 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2 mg/ml (varies by lot)
• Sequence Length: 395

• Applicable Applications for anti-GAS8 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:50-1:200
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human growth arrest-specific 8
• Target Name: GAS8
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/40.)

Related Product Information for anti-GAS8 antibody

This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene.

Product Categories/Family for anti-GAS8 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 555290160
• NCBI GeneID: 2622
• NCBI Accession #: NP_001273134.1
• NCBI GenBank Nucleotide #: NM_001286205.1
• UniProt Accession #: O95995; Q2M234; B2RCT1; B7Z4U1; G3V1L5
• Molecular Weight: 53,809 Da
• NCBI Official Full Name: growth arrest-specific protein 8 isoform b
• NCBI Official Synonym Full Names: growth arrest-specific 8
• NCBI Official Symbol: GAS8
• NCBI Official Synonym Symbols: GAS11
• NCBI Protein Information: growth arrest-specific protein 8
• UniProt Protein Name: Growth arrest-specific protein 8
• Protein Family: Growth arrest-specific protein
• UniProt Gene Name: GAS8
• UniProt Synonym Gene Names: GAS11; GAS-8; GAS-11
• UniProt Entry Name: GAS8_HUMAN

NCBI Description

This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

Uniprot Description

GAS8: Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility. Belongs to the GAS8 family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: Golgi apparatus; microtubule

Molecular Function: Rab GTPase binding

Biological Process: negative regulation of cell proliferation; sperm motility