Rabbit GAS2L1 Polyclonal Antibody | anti-GAS2L1 antibody

GAS2L1 antibody

Cat. Num. AAA9408812

• Gene Names: GAS2L1; GAR22
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: GAS2L1; Polyclonal Antibody; GAS2L1 antibody; GAR22; anti-GAS2L1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total GAS2L1 antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 454

• Applicable Applications for anti-GAS2L1 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:500 - 1:2000
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human GAS2L1.
• Target Name: GAS2L1
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of K562 cell lines, using GAS2L1 antibody.)

Related Product Information for anti-GAS2L1 antibody

The protein encoded by this gene, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells. Expression of the mouse Gas2 gene is negatively regulated by serum and growth factors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Product Categories/Family for anti-GAS2L1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 523525241
• NCBI GeneID: 10634
• NCBI Accession #: NP_001265659.1
• NCBI GenBank Nucleotide #: NM_001278730.1
• UniProt Accession #: Q99501; Q53EN7; Q92640; Q9BUY9; B5MCR7
• Molecular Weight: 48,273 Da
• NCBI Official Full Name: GAS2-like protein 1 isoform c
• NCBI Official Synonym Full Names: growth arrest-specific 2 like 1
• NCBI Official Symbol: GAS2L1
• NCBI Official Synonym Symbols: GAR22
• NCBI Protein Information: GAS2-like protein 1
• UniProt Protein Name: GAS2-like protein 1
• Protein Family: GAS2-like protein
• UniProt Gene Name: GAS2L1
• UniProt Synonym Gene Names: GAR22
• UniProt Entry Name: GA2L1_HUMAN

NCBI Description

This gene encodes a member of the growth arrest-specific 2 protein family. This protein binds components of the cytoskeleton and may be involved in mediating interactions between microtubules and microfilaments. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Jul 2013]

Uniprot Description

GAS2L1: Seems to be involved in the cross-linking of microtubules and microfilaments. Belongs to the GAS2 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: microtubule; cytoskeleton; cytoplasm; stress fiber

Molecular Function: microtubule binding; thyroid hormone receptor binding; cytoskeletal adaptor activity

Biological Process: negative regulation of erythrocyte differentiation; regulation of cell cycle; negative regulation of microtubule depolymerization; negative regulation of cell growth; cell cycle arrest; cellular response to starvation; microtubule bundle formation