Rabbit GAP43 Polyclonal Antibody | anti-GAP43 antibody
RABBIT ANTI GAP43
Reactivity
Human, Monkey, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Synonyms
GAP43; Polyclonal Antibody; RABBIT ANTI GAP43; anti-GAP43 antibody
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Form/Format
Serum
Serum - liquid
Serum - liquid
Sequence Length
242
Applicable Applications for anti-GAP43 antibody
Immunohistology Frozen, Immunofluorescence (IF), Immunoprecipitation (IP), P, Western Blot (WB)
Application Notes
Western Blotting: Minimum Dilution: 1/500; Maximum Dilution: 1/1000
Perservative Stabilisers
0.02% Sodium Azide (NaN3)
Antiserum Preparation
Antisera to GAP43 were raised by repeated immunisations of rabbits with highly purified antigen.
Target Species
Cat
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-GAP43 antibody
Rabbit anti GAP43 antibody recognises the protein designated GAP43, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth. GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilised protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,135 Da
NCBI Official Full Name
neuromodulin
NCBI Official Symbol
GAP43
NCBI Protein Information
neuromodulin; axonal membrane protein GAP-43; growth-associated protein 43
UniProt Protein Name
Neuromodulin
Protein Family
UniProt Gene Name
GAP43
UniProt Entry Name
NEUM_FELCA
Uniprot Description
This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction ().
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Product Notes
The GAP43 gap43 (Catalog #AAA222457) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI GAP43 reacts with Human, Monkey, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GAP43 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Immunofluorescence (IF), Immunoprecipitation (IP), P, Western Blot (WB). Western Blotting: Minimum Dilution: 1/500; Maximum Dilution: 1/1000. Researchers should empirically determine the suitability of the GAP43 gap43 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GAP43, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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