Western Blot (WB)
(Western blot analysis of extracts from Mouse kidney tissue, using GALNT14 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit GALNT14 Polyclonal Antibody | anti-GALNT14 antibody
GALNT14 Antibody
Gene Names
GALNT14; GALNT15; GalNac-T10; GalNac-T14
Reactivity
Human, Mouse, RatPredicted: Pig, Bovine, Sheep, Rabbit, Dog, Chicken
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
GALNT14; Polyclonal Antibody; GALNT14 Antibody; GalNAc T14; GalNAc-T14; Galnt14; GLT14_HUMAN; Polypeptide GalNAc transferase 14; Polypeptide N acetylgalactosaminyltransferase 14; Polypeptide N-acetylgalactosaminyltransferase 14; pp GaNTase 14; pp-GaNTase 14; Protein UDP acetylgalactosaminyltransferase 14; Protein-UDP acetylgalactosaminyltransferase 14; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 14; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14; anti-GALNT14 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Sheep, Rabbit, Dog, Chicken
Predicted: Pig, Bovine, Sheep, Rabbit, Dog, Chicken
Clonality
Polyclonal
Isotype
IgG
Specificity
GALNT14 Antibody detects endogenous levels of GALNT14.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
552
Applicable Applications for anti-GALNT14 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human GALNT14.
Tissue Specificity
Detected in renal tubules (at protein level). Highly expressed in fetal and adult kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bladder, uterus, placenta, testis, ovary, skeletal muscle, leukocyte, B-cell, bone marrow, fetal brain, fetal thymus, fetal lung, fetal liver, fetal small intestine, fetal spleen, fetal skeletal and fetus. Detected in renal tubules (at protein level).
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Golgi Apparatus
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of extracts from Mouse kidney tissue, using GALNT14 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Mouse kidney tissue, using GALNT14 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-GALNT14 antibody
Description: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.
Similarity: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding. The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Similarity: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding. The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 64 kDa
Predicted: 65 kDa
Predicted: 65 kDa
NCBI Official Full Name
polypeptide N-acetylgalactosaminyltransferase 14 isoform 1
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 14
NCBI Official Symbol
GALNT14
NCBI Official Synonym Symbols
GALNT15; GalNac-T10; GalNac-T14
NCBI Protein Information
polypeptide N-acetylgalactosaminyltransferase 14
UniProt Protein Name
Polypeptide N-acetylgalactosaminyltransferase 14
Protein Family
UniProt Gene Name
GALNT14
UniProt Synonym Gene Names
GalNAc-T14; pp-GaNTase 14
UniProt Entry Name
GLT14_HUMAN
NCBI Description
This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Alterations in this gene may play a role in cancer progression and response to chemotherapy. [provided by RefSeq, Jun 2016]
Research Articles on GALNT14
Similar Products
Product Notes
The GALNT14 galnt14 (Catalog #AAA9611781) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GALNT14 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Sheep, Rabbit, Dog, Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's GALNT14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GALNT14 galnt14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GALNT14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
