Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Testing Data

Rabbit anti-Human Galectin-3 Polyclonal Antibody | anti-Lgals3 antibody

Galectin-3 Antibody

Gene Names
Lgals3; L-34; CBP30; gal-3; AGE-R3
Reactivity
Human
Applications
Western Blot
Purity
Affinity purified
Synonyms
Galectin-3; Polyclonal Antibody; Galectin-3 Antibody; LGALS3; L-31; GAL3; GALIG; MAC2; GALBP; LGALS2; MAC-2; CBP35; anti-Lgals3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid
Concentration
0.2 mg/ml (varies by lot)
Sequence Length
262
Applicable Applications for anti-Lgals3 antibody
Western Blot (WB)
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody recognizes the 30 kDa human Galectin-3 in Western blot analysis with Jurkat cell lysate.
Immunogen
Synthetic peptide surrounding amino acid 188 of human Galectin-3
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months

Testing Data

Testing Data
Related Product Information for anti-Lgals3 antibody
Background: Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as well as apoptosis. Galectin-3 encodes a 30-35 kDa protein containing a single carbohydrate binding domain, which binds galactose-containing glycoconjmugates. Upregulated expression of Galectin-3 is involved in cancer progression and metastasis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,202 Da
NCBI Official Full Name
galectin-3
NCBI Official Synonym Full Names
lectin, galactoside-binding, soluble, 3
NCBI Official Symbol
Lgals3
NCBI Official Synonym Symbols
L-34; CBP30; gal-3; AGE-R3
NCBI Protein Information
galectin-3
UniProt Protein Name
Galectin-3
Protein Family
UniProt Gene Name
Lgals3
UniProt Synonym Gene Names
Gal-3; CBP 35
UniProt Entry Name
LEG3_RAT

NCBI Description

lectin molecule that binds IgE; may have role in immune function [RGD, Feb 2006]

Uniprot Description

Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Extracellular matrix; Cell surface; Motility/polarity/chemotaxis

Cellular Component: extracellular matrix; spliceosome; extracellular space; proteinaceous extracellular matrix; cell surface; membrane; cytoplasm; mitochondrial inner membrane; plasma membrane; immunological synapse; nucleus; external side of plasma membrane

Molecular Function: monosaccharide binding; advanced glycation end-product receptor activity; laminin binding; IgE binding; disaccharide binding; chemoattractant activity

Biological Process: neutrophil chemotaxis; extracellular matrix organization and biogenesis; positive regulation of serotonin secretion; RNA splicing; negative regulation of endocytosis; regulation of T cell proliferation; negative regulation of T cell receptor signaling pathway; signal transduction; macrophage chemotaxis; monocyte chemotaxis; positive regulation of angiogenesis; epithelial cell differentiation; positive chemotaxis; positive regulation of cell proliferation; eosinophil chemotaxis; innate immune response; mRNA processing; skeletal development; negative regulation of apoptosis

Research Articles on Lgals3

Similar Products

Product Notes

The Lgals3 lgals3 (Catalog #AAA840402) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Galectin-3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Galectin-3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody recognizes the 30 kDa human Galectin-3 in Western blot analysis with Jurkat cell lysate. Researchers should empirically determine the suitability of the Lgals3 lgals3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Galectin-3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.