anti-Mouse Galanin Receptor 3 Polyclonal Antibody | anti-GALR3 antibody
Anti - Galanin Receptor 3 (GALR3)
Gene Names
GALR3; GALR3
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
Galanin Receptor 3; Polyclonal Antibody; Anti - Galanin Receptor 3 (GALR3); Galanin Receptor 3 (GALR3); anti-GALR3 antibody
Host
Host: Rabbit
Source: Mouse
Source: Mouse
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Mouse peptide sequence has 100% homology with rat (20/20 aa; 100%) and human (16/20 aa; 80%) GALR3. No significant homology of is seen with GLAR1, GALR2 or any other G-protein coupled receptors. Antibody crossreactivity with GALR3 from various species is not known.
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Affinity Purified
Supplied as liquid in PBS, pH 7.4, containing 0.1% BSA and 40% glycerol.
Supplied as liquid in PBS, pH 7.4, containing 0.1% BSA and 40% glycerol.
Concentration
~1mg/ml (varies by lot)
Sequence Length
368
Applicable Applications for anti-GALR3 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA and Western Blot. Other applications not tested.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide per well
Western Blot: 1-10ug/ml using ECL technique.
Optimal dilutions to be determined by the researcher.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide per well
Western Blot: 1-10ug/ml using ECL technique.
Optimal dilutions to be determined by the researcher.
Immunogen
A 20 aa peptide sequence within the cytoplasmic, C-terminus of mouse GLAR3 (1) was coupled to KLH.
Note
The appropriate control immunogenic peptide ((G1043-15H) is available to confirm specificity of antibodies.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-GALR3 antibody
Galanin is a 29 aa C-terminally amidated (30 aa, non-amidated in humans), highly conserved but unique neuroendocrine peptide originally isolated from intestine. The first 14 aa are fully conserved in almost all species. Galanin is found in the brain and the gut. It modulates a variety of physiological processed including cognition/memory, sensory/pain processing, neurotransmitter/hormone secretion, and feeding behavior. Several N-terminally elongated (-7-29 and -9-29) or truncated biologically active forms of galanin have also been isolated. Galanin antagonists are chimeric peptides generated by linking the amino terminal portion of galanin to substance P (galantide, M15), bradykinin (M35), the neurokinin antagonist spantide (C7) or an idealized alpha helical region (M40) (see review in refs 2 by Kask et al 1995).
Product Categories/Family for anti-GALR3 antibody
References
• (1.) Kolakowski LF et al (1998) Gene Accession # AF042783(2.) Smith KE et al (1998) JBC 273, 2321-23326; Wang S et al (1997) JBC 272, 31949-31952;. Pharmacol. 52, 337-343; Fathi Z et al (198) Mol Brain Res. 58, 156-169
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,573 Da
NCBI Official Full Name
galanin receptor type 3
NCBI Official Synonym Full Names
galanin receptor 3
NCBI Official Symbol
GALR3
NCBI Official Synonym Symbols
GALR3
NCBI Protein Information
galanin receptor type 3; GAL3-R; GALR-3; OTTHUMP00000198159; galanin receptor, family member 3
UniProt Protein Name
Galanin receptor type 3
Protein Family
UniProt Gene Name
GALR3
UniProt Synonym Gene Names
GALNR3
UniProt Entry Name
GALR3_HUMAN
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Product Notes
The GALR3 galr3 (Catalog #AAA621237) is an Antibody produced from Host: Rabbit Source: Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti - Galanin Receptor 3 (GALR3) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Galanin Receptor 3 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA and Western Blot. Other applications not tested. Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide per well Western Blot: 1-10ug/ml using ECL technique. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the GALR3 galr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Galanin Receptor 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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