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Western Blot (WB) (Western blotAll lanes: GABRR1 antibody at 1.25ug/ml+mouse eye tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 56,54,46 kDaObserved band size: 56 kDa)

Rabbit anti-Human, Mouse GABRR1 Polyclonal Antibody | anti-GABRR1 antibody

GABRR1 Antibody

Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
GABRR1; Polyclonal Antibody; GABRR1 Antibody; Gamma-aminobutyric acid receptor subunit rho-1; GABA(A) receptor subunit rho-1; GABA(C) receptor; anti-GABRR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
462
Applicable Applications for anti-GABRR1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Gamma-aminobutyric acid receptor subunit rho-1 protein (365-465AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22960 / sc-21336 / sc-31452 / sc-16879 / sc-21338 / sc-25707
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: GABRR1 antibody at 1.25ug/ml+mouse eye tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 56,54,46 kDaObserved band size: 56 kDa)

Western Blot (WB) (Western blotAll lanes: GABRR1 antibody at 1.25ug/ml+mouse eye tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 56,54,46 kDaObserved band size: 56 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human tonsil tissue using MBS7043674 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human tonsil tissue using MBS7043674 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human thymus using MBS7043674 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human thymus using MBS7043674 at dilution 1:100)
Related Product Information for anti-GABRR1 antibody
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,516 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit rho-1 isoform b
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor rho1 subunit
NCBI Official Symbol
GABRR1
NCBI Protein Information
gamma-aminobutyric acid receptor subunit rho-1
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit rho-1
UniProt Gene Name
GABRR1
UniProt Entry Name
GBRR1_HUMAN

NCBI Description

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Uniprot Description

GABRR1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, integral; Receptor, misc.; Membrane protein, multi-pass; Channel, ligand-gated; Transporter, ion channel; Channel, chloride

Chromosomal Location of Human Ortholog: 6q15

Cellular Component: integral to plasma membrane; plasma membrane

Biological Process: gamma-aminobutyric acid signaling pathway; synaptic transmission; transport

Research Articles on GABRR1

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Product Notes

The GABRR1 gabrr1 (Catalog #AAA7043674) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GABRR1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GABRR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the GABRR1 gabrr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABRR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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