Western Blot (WB)
(GABRR1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GABRR1 antibody detected the GABRR1 protein (arrow).)
Rabbit anti-Human GABRR1 Polyclonal Antibody | anti-GABRR1 antibody
GABRR1 Antibody (N-term)
Western Blot (WB)
(GABRR1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GABRR1 antibody detected the GABRR1 protein (arrow).)
Western Blot (WB)
(GABRR1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GABRR1 antibody detected the GABRR1 protein (arrow).)
mammalian brain where it acts at GABA receptors, which are
ligand-gated chloride channels. GABRR1 is a member of the rho
subunit family.
Green, E.K., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2010) In press :
Reyes-Ruiz, J.M., et al. Biochim. Biophys. Acta 1798(5):1002-1007(2010)
Xuei, X., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (2), 418-427 (2010) :
Kang, J.Q., et al. Trends Mol Med 15(9):430-438(2009)
NCBI and Uniprot Product Information
NCBI Description
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Uniprot Description
GABRR1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.; Membrane protein, multi-pass; Transporter; Membrane protein, integral; Channel, chloride; Transporter, ion channel; Channel, ligand-gated
Chromosomal Location of Human Ortholog: 6q15
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction
Molecular Function: chloride channel activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity
Biological Process: synaptic transmission; transport; transmembrane transport; gamma-aminobutyric acid signaling pathway
Research Articles on GABRR1
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Product Notes
The GABRR1 gabrr1 (Catalog #AAA9200907) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-48. The GABRR1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GABRR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GABRR1 gabrr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABRR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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