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Western Blot (WB) (Western Blot analysis of MOUSE-BRAIN cells using GABAA Ralpha6 Polyclonal Antibody)

Rabbit GABRA6 Polyclonal Antibody | anti-GABRA6 antibody

GABRA6 Antibody

Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
GABRA6; Polyclonal Antibody; GABRA6 Antibody; Gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6; anti-GABRA6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Applicable Applications for anti-GABRA6 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:40000
Immunogen
Synthesized peptide derived from the Internal region of human GABAA Ralpha6.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of MOUSE-BRAIN cells using GABAA Ralpha6 Polyclonal Antibody)

Western Blot (WB) (Western Blot analysis of MOUSE-BRAIN cells using GABAA Ralpha6 Polyclonal Antibody)

Western Blot (WB)

(Western Blot analysis of MOUSE-BRAIN cells using GABAA Ralpha6 Polyclonal Antibody)

Western Blot (WB) (Western Blot analysis of MOUSE-BRAIN cells using GABAA Ralpha6 Polyclonal Antibody)
Product Categories/Family for anti-GABRA6 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,024 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit alpha-6
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) A receptor, alpha 6
NCBI Official Symbol
GABRA6
NCBI Protein Information
gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor, alpha 6; GABA subunit A receptor alpha 6; GABA(A) receptor subunit alpha-6
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit alpha-6
UniProt Gene Name
GABRA6
UniProt Entry Name
GBRA6_HUMAN

NCBI Description

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

GABRA6: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.

Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, ion channel; Channel, chloride

Chromosomal Location of Human Ortholog: 5q34

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction

Molecular Function: chloride channel activity; GABA-A receptor activity; benzodiazepine receptor activity; extracellular ligand-gated ion channel activity

Biological Process: synaptic transmission; transport; signal transduction; transmembrane transport; gamma-aminobutyric acid signaling pathway

Research Articles on GABRA6

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Product Notes

The GABRA6 gabra6 (Catalog #AAA7122028) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GABRA6 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GABRA6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:40000. Researchers should empirically determine the suitability of the GABRA6 gabra6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABRA6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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