Rabbit anti-Human, Mouse GABPB1 Polyclonal Antibody | anti-GABPB1 antibody

GABPB1 Polyclonal Antibody

Cat. Num. AAA2562830

• Gene Names: GABPB1; E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-53
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: GABPB1; Polyclonal Antibody; GABPB1 Polyclonal Antibody; BABPB2; E4TF1; E4TF1-47; E4TF1-53; E4TF1B; GA binding protein transcription factor beta subunit 1 transcript variant gamma 2; GA binding protein transcription factor; beta subunit 1; beta subunit 2; GA-binding protein subunit beta-1; GABP subunit beta-1; GABP subunit beta-2; GABP1; GABPB; GABPB-1; GABPB-2; GABPB2; NRF2B1; NRF2B2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53; anti-GABPB1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.96mg/mL (varies by lot)
• Sequence Length: 395

• Applicable Applications for anti-GABPB1 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:50-1:300; ELISA: 1:5000-1:10000
• Immunogen: Fusion protein of human GABPB1
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using GABPB1 Polyclonal Antibody at dilution of 1:55(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using GABPB1 Polyclonal Antibody at dilution of 1:55(×200))

Related Product Information for anti-GABPB1 antibody

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Product Categories/Family for anti-GABPB1 antibody

Cancer; Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 8051593
• NCBI GeneID: 2553
• NCBI Accession #: NP_005245.2; BC036080
• NCBI GenBank Nucleotide #: NP_005245.2
• UniProt Accession #: Q06547
• NCBI Official Full Name: GA-binding protein subunit beta-1 isoform beta 1
• NCBI Official Synonym Full Names: GA binding protein transcription factor subunit beta 1
• NCBI Official Symbol: GABPB1
• NCBI Official Synonym Symbols: E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-53
• NCBI Protein Information: GA-binding protein subunit beta-1
• UniProt Protein Name: GA-binding protein subunit beta-1
• Protein Family: GA-binding protein
• UniProt Gene Name: GABPB1
• UniProt Synonym Gene Names: E4TF1B; GABPB; GABPB2; GABP subunit beta-1; GABPB-1; GABPB-2
• UniProt Entry Name: GABP1_HUMAN

NCBI Description

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

GABPB1: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; protein heterodimerization activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; transcription, DNA-dependent; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter