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Western Blot (WB) (Western Blot analysis of GABPB1 in A549 cell lysate using GABPB1 Rabbit pAb at dilution 1/1000)

Rabbit anti-Human, Mouse GABPB1 Polyclonal Antibody | anti-GABPB1 antibody

GABPB1 Rabbit pAb

Gene Names
GABPB1; E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; E4TF1-47; E4TF1-53
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
GABPB1; Polyclonal Antibody; GABPB1 Rabbit pAb; GA binding protein transcription factor beta subunit 1; E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-53; anti-GABPB1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.2mg/ml (varies by lot)
Applicable Applications for anti-GABPB1 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:1000-1:5000
IHC-P: 1:70-1:350
Immunogen
Fusion protein of human GABPB1
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of GABPB1 in A549 cell lysate using GABPB1 Rabbit pAb at dilution 1/1000)

Western Blot (WB) (Western Blot analysis of GABPB1 in A549 cell lysate using GABPB1 Rabbit pAb at dilution 1/1000)

Immunohistochemistry (IHC)

(Immunohistochemistry of GABPB1 in paraffin-embedded Human esophagus cancer tissue using GABPB1 Rabbit pAb at dilution 1/70. Predicted cell location: Nucleus)

Immunohistochemistry (IHC) (Immunohistochemistry of GABPB1 in paraffin-embedded Human esophagus cancer tissue using GABPB1 Rabbit pAb at dilution 1/70. Predicted cell location: Nucleus)
Related Product Information for anti-GABPB1 antibody
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,950 Da
NCBI Official Full Name
GA-binding protein subunit beta-1 isoform beta 1
NCBI Official Synonym Full Names
GA binding protein transcription factor, beta subunit 1
NCBI Official Symbol
GABPB1
NCBI Official Synonym Symbols
E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; E4TF1-47; E4TF1-53
NCBI Protein Information
GA-binding protein subunit beta-1; GABPB-1; GABP subunit beta-2; nuclear respiratory factor 2; transcription factor E4TF1-47; transcription factor E4TF1-53; GA binding protein transcription factor beta subunit 1 transcript variant gamma-2
UniProt Protein Name
GA-binding protein subunit beta-1
Protein Family
UniProt Gene Name
GABPB1
UniProt Synonym Gene Names
E4TF1B; GABPB; GABPB2; GABP subunit beta-1; GABPB-1; GABPB-2
UniProt Entry Name
GABP1_HUMAN

NCBI Description

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

GABPB1: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; protein heterodimerization activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; transcription, DNA-dependent; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter

Research Articles on GABPB1

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Product Notes

The GABPB1 gabpb1 (Catalog #AAA4759304) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GABPB1 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GABPB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:1000-1:5000 IHC-P: 1:70-1:350. Researchers should empirically determine the suitability of the GABPB1 gabpb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABPB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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