Rabbit anti-Human, Rat GABARAP Polyclonal Antibody | anti-GABARAP antibody

Anti-GABARAP Antibody

Cat. Num. AAA4152724

• Gene Names: GABARAP; MM46; ATG8A; GABARAP-a
• Reactivity: Human, Rat
• Applications: Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Western Blot
• Purity: Filter purified
• Synonyms: GABARAP; Polyclonal Antibody; Anti-GABARAP Antibody; anti-GABARAP antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Purity/Purification: Filter purified
• Form/Format: Liquid
• Concentration: 1ug/ul (varies by lot)
• Sequence Length: 117

• Applicable Applications for anti-GABARAP antibody: Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)
• Application Notes: A dilution of 1:200 to 1:1000 dilution is recommended for these applications.
• Immunogen: A synthetic peptide corresponding to the N-terminal of human GABARAP protein has been used as the immunogen. The sequence is homologous with mouse and rat form of GABARAP.
• Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide.
• Preparation and Storage: This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.; For extended storage, aliquot contents and freeze at -20 degree C or below.; Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

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Related Product Information for anti-GABARAP antibody

GABARAP is highly positively charged in its N-terminus and shares sequence homology with MAP1LC3 1A and 1B. This protein clusters neurotransmitter receptors (GABA(A) receptors) by mediating interaction with the cytoskeleton. SUBUNIT: Interacts with GABRG2, TUBA1, ULK1 and NSF. Interacts with beta-tubulin and GPHN. SUBCELLULAR LOCATION: Intracytoplasmic membrane. Cytoskeleton. Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules. TISSUE SPECIFICITY: Heart, brain, placenta, skeletal muscle, kidney and pancreas.

NCBI and Uniprot Product Information

• NCBI GI #: 6005764
• NCBI GeneID: 11337
• NCBI Accession #: NP_009209.1
• NCBI GenBank Nucleotide #: NM_007278.1
• UniProt Accession #: O95166
• Molecular Weight: 13,918 Da
• NCBI Official Full Name: gamma-aminobutyric acid receptor-associated protein
• NCBI Official Synonym Full Names: GABA type A receptor-associated protein
• NCBI Official Symbol: GABARAP
• NCBI Official Synonym Symbols: MM46; ATG8A; GABARAP-a
• NCBI Protein Information: gamma-aminobutyric acid receptor-associated protein
• UniProt Protein Name: Gamma-aminobutyric acid receptor-associated protein
• Protein Family: Gamma-aminobutyric acid receptor-associated protein
• UniProt Gene Name: GABARAP
• UniProt Synonym Gene Names: FLC3B

NCBI Description

Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008]

Uniprot Description

Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.