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Western Blot (WB) (Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue with GABA Transporter 1 Rabbit pAb EA290 diluted at 1:2,000.)

Rabbit GABA Transporter 1 Polyclonal Antibody | anti-GABA antibody

GABA Transporter 1 Rabbit pAb

Gene Names
SLC6A1; GAT1; GABATR; GABATHG
Reactivity
Human, Rat, Mouse
Synonyms
GABA Transporter 1; Polyclonal Antibody; GABA Transporter 1 Rabbit pAb; GAT1;GABATHG;GABATR;SC6A1; anti-GABA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Form/Format
PBS with 0.02% sodium azide and 50% glycerol pH7.4.
Concentration
1mg/ml (varies by lot)
Species
Human
Immunogen
Synthetic Peptide
Preparation and Storage
Store at -20 degree C. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue with GABA Transporter 1 Rabbit pAb EA290 diluted at 1:2,000.)

Western Blot (WB) (Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue with GABA Transporter 1 Rabbit pAb EA290 diluted at 1:2,000.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using GABA Transporter 1 (EA290)Rabbit pAb diluted at 1:200.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using GABA Transporter 1 (EA290)Rabbit pAb diluted at 1:200.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using GABA Transporter 1 (EA290)Rabbit pAb diluted at 1:200.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using GABA Transporter 1 (EA290)Rabbit pAb diluted at 1:200.)
Related Product Information for anti-GABA antibody
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,074 Da
NCBI Official Full Name
sodium- and chloride-dependent GABA transporter 1
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
NCBI Official Symbol
SLC6A1
NCBI Official Synonym Symbols
GAT1; GABATR; GABATHG
NCBI Protein Information
sodium- and chloride-dependent GABA transporter 1; GAT-1; solute carrier family 6 member 1
UniProt Protein Name
Sodium- and chloride-dependent GABA transporter 1
Protein Family
UniProt Gene Name
SLC6A1
UniProt Synonym Gene Names
GABATR; GABT1; GAT1; GAT-1
UniProt Entry Name
SC6A1_HUMAN

NCBI Description

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009]

Uniprot Description

SLC6A1: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: cell surface; membrane; integral to plasma membrane; axon; plasma membrane; integral to membrane

Molecular Function: gamma-aminobutyric acid:sodium symporter activity; neurotransmitter:sodium symporter activity

Biological Process: response to purine; response to toxin; neurotransmitter secretion; learning; response to cocaine; response to estradiol stimulus; response to sucrose stimulus; synaptic transmission; transport; response to lead ion; gamma-aminobutyric acid import; negative regulation of synaptic transmission, GABAergic; response to calcium ion; transmembrane transport; protein homooligomerization; positive regulation of gamma-aminobutyric acid secretion

Disease: Myoclonic-atonic Epilepsy

Research Articles on GABA

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Product Notes

The GABA slc6a1 (Catalog #AAA8808400) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GABA Transporter 1 Rabbit pAb reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "GABA Transporter 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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