Testing Data
Rabbit anti-Rat GABA (A) a6 Polyclonal Antibody
Anti-GABA (A) a6 Antibody
Reactivity
Rat
Applications
Western Blot
Purity
Affinity Purified On Immobilized Antigen.
Synonyms
GABA (A) a6; Polyclonal Antibody; Anti-GABA (A) a6 Antibody; GABAA Receptor (alpha6 subunit); anti-GABA (A) a6 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified On Immobilized Antigen.
Form/Format
Liquid; PBS, pH 7.4 with 0.05% sodium azide.
Concentration
1ug/ul (varies by lot)
Applicable Applications for anti-GABA (A) a6 antibody
Western Blot (WB)
Immunogen
Peptide QLEDEGNFYSENVSRILDN(C) corresponding to amino acid residues 20-37 of rat GABA(A) a6 (Accession number P30191).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Testing Data
Testing Data
Related Product Information for anti-GABA (A) a6 antibody
GABA (g-aminobutyric acid) is the major inhibitory neurotransmitter in the brain. Its production, release, reuptake and metabolism occur in the nervous system.1 The GABA transmitter interacts with two major types of receptors: ionotropic GABAA (GABAAR) and the metabotropic GABAB) receptors. The GABAAR belongs to the ligand gated ion channel superfamily.2 The GABAAR, is a heteropentamer, with all of its five subunits contributing to the pore formation. To date, eight subunit isoforms were cloned: a, b, g, d, e, P, q, and r.1 Six a subunit isoforms were described to exist in mammals (a1-a6). The native GABAA receptor, in most cases, consists of 2a, 2b and 1g subunit. The a subunit is the most common subunit and is expressed ubiquitously. It determines the affinities for allosteric ligands shown by GABAAR. A possible role for the GABAA receptors in alcohol action has been derived from animal studies, in vitro cell models and human research which suggested an important role for GABAA a6 along with b2, a1 and g2, in alcohol related phenotypes.3 In Canavan disease (inherited leukodystrophy), low level of expression of GABAA a6 was reported.4
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Product Notes
The GABA (A) a6 (Catalog #AAA4157614) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GABA (A) a6 Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GABA (A) a6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the GABA (A) a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABA (A) a6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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