Western Blot (WB)
(Western blot analysis of FRS2 expression with rat kidney tissue lysates.)
Rabbit FRS2 Polyclonal Antibody | anti-FRS2 antibody
FRS2 Antibody
Gene Names
FRS2; SNT; SNT1; FRS1A; FRS2A; SNT-1; FRS2alpha
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
FRS2; Polyclonal Antibody; FRS2 Antibody; Rabbit Polyclonal FRS2 Antibody; Polyclonal FRS2 antibody; anti-FRS2 antibody; FRS-2 antibody; SNT antibody; FRS 2 antibody; FRS2A antibody; SNT-1 antibody; FRS-2; FRS 2; FRS2 alpha antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer containing 30% Glycerol, 0.5% BSA, and 0.01% Thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
512
Applicable Applications for anti-FRS2 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Immunogen
FRS2 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 493 of human FRS2 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of FRS2 expression with rat kidney tissue lysates.)
Western Blot (WB)
(Western blot analysis of FRS2 expression with rat kidney tissue lysates.)
Related Product Information for anti-FRS2 antibody
Fibroblast growth factor receptor substrate 2 is a 70-90kDA member of the FSR family of lipid-anchored docking protein. FRS2 contains Grb2 binding sites, a myristylation sequence and a PTP domain. Activation of FGFR leads to tyrosine phosphorylation of FRS2 and the binding of phosphorylated FRS2 to GRB2/SOS complexes. Once phosphorylated, FRS2 recruits SH2 domain-containing proteins including Grb2 and SHP-2 mediating downstream signalling. FRS2 thus, acts as an intermediary between FGF and Trk receptors that links receptor tyrosine kinase to Ras/MAPK signaling pathway.
Product Categories/Family for anti-FRS2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
FRS2 protein
NCBI Official Synonym Full Names
fibroblast growth factor receptor substrate 2
NCBI Official Symbol
FRS2
NCBI Official Synonym Symbols
SNT; SNT1; FRS1A; FRS2A; SNT-1; FRS2alpha
NCBI Protein Information
fibroblast growth factor receptor substrate 2
Protein Family
Research Articles on FRS2
Similar Products
Product Notes
The FRS2 (Catalog #AAA5311505) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FRS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the FRS2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FRS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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