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Western Blot (WB) (Western blot analysis of lysates from K562 cell line, mouse small intestine, rat stomach tissue lysate(from left to right), using Frk Antibody (C-term). MBS9210226 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)

Rabbit Frk Polyclonal Antibody | anti-Frk antibody

Mouse Frk Antibody (C-term)

Gene Names
Frk; BSK; GTK; RAK; C85044; BSK/IYK
Reactivity
Human, mouse, rat
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Frk; Polyclonal Antibody; Mouse Frk Antibody (C-term); Tyrosine-protein kinase FRK; Beta-cell Src-homology tyrosine kinase; BSK; FYN-related kinase; Intestine tyrosine kinase; Bsk; Iyk; anti-Frk antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Frk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 482-516 amino acids from the C-terminal region of human Mouse Frk.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.422 (varies by lot)
Sequence Length
512
Applicable Applications for anti-Frk antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:500-1:1000
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of lysates from K562 cell line, mouse small intestine, rat stomach tissue lysate(from left to right), using Frk Antibody (C-term). MBS9210226 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)

Western Blot (WB) (Western blot analysis of lysates from K562 cell line, mouse small intestine, rat stomach tissue lysate(from left to right), using Frk Antibody (C-term). MBS9210226 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Related Product Information for anti-Frk antibody
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
Product Categories/Family for anti-Frk antibody
References
Thuveson M.,et al.Biochem. Biophys. Res. Commun. 209:582-589(1995).
Oberg-Welsh C.,et al.Gene 152:239-242(1995).
Carninci P.,et al.Science 309:1559-1563(2005).
Chandrasekharan S.,et al.Mol. Cell. Biol. 22:5235-5247(2002).
Welsh M.,et al.Biochem. J. 382:261-268(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58844
NCBI Official Full Name
tyrosine-protein kinase FRK
NCBI Official Synonym Full Names
fyn-related kinase
NCBI Official Symbol
Frk
NCBI Official Synonym Symbols
BSK; GTK; RAK; C85044; BSK/IYK
NCBI Protein Information
tyrosine-protein kinase FRK
UniProt Protein Name
Tyrosine-protein kinase FRK
Protein Family
UniProt Gene Name
Frk
UniProt Synonym Gene Names
Bsk; Iyk; BSK
UniProt Entry Name
FRK_MOUSE

Uniprot Description

FRK: a tyrosine kinase of the Src family. Expressed in cell lines derived from tissues of lymphoid, brain, breast, colon and bladder origin. A nuclear protein that may function during G1 and S phase of the cell cycle to suppress growth.

Protein type: EC 2.7.10.2; Kinase, protein; Protein kinase, tyrosine (non-receptor); Tumor suppressor; Protein kinase, TK; TK group; Src family

Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm; plasma membrane; nucleus

Molecular Function: transferase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; non-membrane spanning protein tyrosine kinase activity; kinase activity; ATP binding; protein kinase activity; receptor binding

Biological Process: cell migration; innate immune response; cell differentiation; actin cytoskeleton organization and biogenesis; phosphorylation; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation

Research Articles on Frk

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Product Notes

The Frk frk (Catalog #AAA9210226) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mouse Frk Antibody (C-term) reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Frk can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:500-1:1000. Researchers should empirically determine the suitability of the Frk frk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Frk, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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