Goat FRAG1 Polyclonal Antibody | anti-Atad5 antibody

Goat anti-FRAG1 (mouse) Antibody

Cat. Num. AAA420637

• Gene Names: Atad5; Gm17; FRAG1; C130052G03Rik
• Reactivity: Expected from sequence similarity: Mouse, Rat
• Applications: ELISA
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: FRAG1; Polyclonal Antibody; Goat anti-FRAG1 (mouse) Antibody; Atad5; ATPase family; AAA domain containing 5; C17orf41; chromosome 17 open reading frame 41; FLJ12735; chromosome fragility associated gene 1; hypothetical protein LOC237877; RP23-328O2.1; C130052G03Rik; Atad5 antibody; AAA domain containing 5 antibody; C17orf41 antibody; chromosome 17 open reading frame 41 antibody; FLJ12735 antibody; FRAG1 antibody; chromosome fragility associated gene 1 antibody; hypothetical protein LOC237877 antibody; RP23-328O2.1 antibody; C130052G03Rik antibody; FRAG1 (mouse); anti-Atad5 antibody

• Host: Goat
• Reactivity: Expected from sequence similarity: Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: QSKDQPLRKSQK
• Sequence Length: 1826

• Applicable Applications for anti-Atad5 antibody: Peptide ELISA (EIA)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 64000.; Western Blot: Preliminary experiments gave an approx 60kDa band in lysates of cell lines NIH3T3 and NSO after 0. 01ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 204kDa according to NP_001025027.1. The 60kDa band was successfully blocked by incubation with the immunizing peptide.
• Immunogen: Peptide with sequence C-QSKDQPLRKSQK, from the internal region of the protein sequence according to NP_001025027.1.
• Epitope: Internal region
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

• NCBI GI #: 71143102
• NCBI GeneID: 237877
• NCBI Accession #: NP_001025027.1
• NCBI GenBank Nucleotide #: NM_001029856.2
• Molecular Weight: 90,207 Da
• NCBI Official Full Name: ATPase family AAA domain-containing protein 5
• NCBI Official Synonym Full Names: ATPase family, AAA domain containing 5
• NCBI Official Symbol: Atad5
• NCBI Official Synonym Symbols: Gm17; FRAG1; C130052G03Rik
• NCBI Protein Information: ATPase family AAA domain-containing protein 5
• UniProt Protein Name: ATPase family AAA domain-containing protein 5
• Protein Family: ATPase family AAA domain-containing protein
• UniProt Gene Name: Atad5
• UniProt Synonym Gene Names: Frag1
• UniProt Entry Name: ATAD5_MOUSE

Uniprot Description

ATAD5: Involved in DNA damage response. Involved in a RAD9A- related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages- induced apoptosis. Belongs to the AAA ATPase family. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: nucleus

Molecular Function: ATP binding; nucleotide binding

Biological Process: response to DNA damage stimulus