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Western Blot (WB) (Western blot analysis of extracts from K562 cells, HUVEC cells and COLO cells, using CDC40 antibody.)

Rabbit CDC40 Polyclonal Antibody | anti-CDC40 antibody

CDC40 Antibody

Gene Names
CDC40; EHB3; PRP17; PRPF17
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CDC40; Polyclonal Antibody; CDC40 Antibody; cell division cycle 40; EH-binding protein 3; EHB3; pre-mRNA splicing factor 17; pre-mRNA-processing factor 17; anti-CDC40 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CDC40 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
579
Applicable Applications for anti-CDC40 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human CDC40.
Target Name
CDC40
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from K562 cells, HUVEC cells and COLO cells, using CDC40 antibody.)

Western Blot (WB) (Western blot analysis of extracts from K562 cells, HUVEC cells and COLO cells, using CDC40 antibody.)
Related Product Information for anti-CDC40 antibody
Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.Zhou Z., EMBO J. 17:2095-2106(1998).Lindsey L.A., J. Biol. Chem. 273:32771-32775(1998).Mungall A.J., Nature 425:805-811(2003).
Product Categories/Family for anti-CDC40 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,521 Da
NCBI Official Full Name
pre-mRNA-processing factor 17
NCBI Official Synonym Full Names
cell division cycle 40
NCBI Official Symbol
CDC40
NCBI Official Synonym Symbols
EHB3; PRP17; PRPF17
NCBI Protein Information
pre-mRNA-processing factor 17
UniProt Protein Name
Pre-mRNA-processing factor 17
UniProt Gene Name
CDC40
UniProt Synonym Gene Names
EHB3; PRP17; PRPF17; Ehb3; hPRP17
UniProt Entry Name
PRP17_HUMAN

NCBI Description

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]

Uniprot Description

CDC40: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.

Protein type: RNA splicing; Motility/polarity/chemotaxis; RNA processing; Spliceosome

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: nucleoplasm; spliceosome

Molecular Function: protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA export from nucleus; RNA splicing; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription

Research Articles on CDC40

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Product Notes

The CDC40 cdc40 (Catalog #AAA9409497) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDC40 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDC40 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the CDC40 cdc40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDC40, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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