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Western Blot (WB) (Western blot analysis of FPR1 expression in A549 (A), Raw264.7 (B), rat brain (C) whole cell lysates.)

Rabbit FPR1 Polyclonal Antibody | anti-FPR1 antibody

Anti-FPR1 Antibody

Gene Names
FPR1; FPR; FMLP
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
FPR1; Polyclonal Antibody; Anti-FPR1 Antibody; fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor; anti-FPR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of FPR1 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
350
Applicable Applications for anti-FPR1 antibody
Western Blot (WB)
Application Notes
WB (1/500 - 1/1000)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FPR1. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of FPR1 expression in A549 (A), Raw264.7 (B), rat brain (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of FPR1 expression in A549 (A), Raw264.7 (B), rat brain (C) whole cell lysates.)
Related Product Information for anti-FPR1 antibody
Rabbit polyclonal antibody to FPR1

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,446 Da
NCBI Official Full Name
fMet-Leu-Phe receptor
NCBI Official Synonym Full Names
formyl peptide receptor 1
NCBI Official Symbol
FPR1
NCBI Official Synonym Symbols
FPR; FMLP
NCBI Protein Information
fMet-Leu-Phe receptor; fMLP receptor; N-formylpeptide chemoattractant receptor
UniProt Protein Name
fMet-Leu-Phe receptor
Protein Family
UniProt Gene Name
FPR1
UniProt Synonym Gene Names
fMLP receptor; FPR
UniProt Entry Name
FPR1_HUMAN

NCBI Description

This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]

Uniprot Description

FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to membrane; plasma membrane; endosome

Molecular Function: protein binding; RAGE receptor binding; N-formyl peptide receptor activity; receptor activity

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; activation of MAPK activity; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); chemotaxis; cell motility; signal transduction; nitric oxide mediated signal transduction

Research Articles on FPR1

Similar Products

Product Notes

The FPR1 fpr1 (Catalog #AAA821370) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FPR1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FPR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the FPR1 fpr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FPR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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