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Testing Data

Rabbit FOXRED2 Polyclonal Antibody | anti-FOXRED2 antibody

Anti-FOXRED2 Antibody

Gene Names
FOXRED2; ERFAD
Reactivity
Human. Predicted: Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
FOXRED2; Polyclonal Antibody; Anti-FOXRED2 Antibody; anti-FOXRED2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human. Predicted: Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
3200
Applicable Applications for anti-FOXRED2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal FOXRED2 (1) antibody was raised against a recombinated human FOXRED2 protein 77-258aa (BC015726).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Testing Data
References
(1) Riemer,J., Appenzeller-Herzog,C., Johansson,L., et al. A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proc. Natl. Acad. Sci. U.S.A. 106 (35), 14831-14836 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
41,157 Da
NCBI Official Full Name
Homo sapiens FAD-dependent oxidoreductase domain containing 2, mRNA
NCBI Official Synonym Full Names
FAD-dependent oxidoreductase domain containing 2
NCBI Official Symbol
FOXRED2
NCBI Official Synonym Symbols
ERFAD
NCBI Protein Information
FAD-dependent oxidoreductase domain-containing protein 2; endoplasmic reticulum flavoprotein associated with degradation
UniProt Protein Name
FAD-dependent oxidoreductase domain-containing protein 2
UniProt Gene Name
FOXRED2
UniProt Entry Name
FXRD2_HUMAN

Uniprot Description

FOXRED2: Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Belongs to the FOXRED2 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 22q12.3

Cellular Component: endoplasmic reticulum lumen

Molecular Function: protein binding; FAD binding; oxidoreductase activity; glycoprotein binding

Biological Process: ER-associated protein catabolic process

Research Articles on FOXRED2

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Product Notes

The FOXRED2 foxred2 (Catalog #AAA416850) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FOXRED2 Antibody reacts with Human. Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FOXRED2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the FOXRED2 foxred2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXRED2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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