Testing Data #1
(Western blot analysis of A20 mouse B cell lymphoma lysate probed with Rabbit anti Human FOXO3A (MBS224281) at 0.5 (A) and 1.0 (B) μgml-1)
Rabbit anti-Mouse, Rat FOXO3A Polyclonal Antibody | anti-FOXO3A antibody
RABBIT ANTI FOXO3A
FOXO3A is ubiquitously expressed and is an important regulator of apoptosis and the cell cycle. FOXO3A triggers apoptosis by inducing the expression of genes necessary for cell death.
Purified IgG - liquid
Western Blot: This item detects a band of approximately 96 kDa in A-20 cell lysates.
Immunohistology - Frozen: Minimum Dilution: 4ug/ml
Western Blotting: Minimum Dilution: 0.5-1ug/ml
Preparation
Histology Positive Control Tissue
Shelf Life: 18 months from date of despatch.
Testing Data #1
(Western blot analysis of A20 mouse B cell lymphoma lysate probed with Rabbit anti Human FOXO3A (MBS224281) at 0.5 (A) and 1.0 (B) μgml-1)
Testing Data #1
(Western blot analysis of A20 mouse B cell lymphoma lysate probed with Rabbit anti Human FOXO3A (MBS224281) at 0.5 (A) and 1.0 (B) μgml-1)
Testing Data #2
(Imunocytochemical staining of A-20 mouse B cell lymphoma cells with Rabbit anti Human FOXO3A (MBS224281))
Testing Data #2
(Imunocytochemical staining of A-20 mouse B cell lymphoma cells with Rabbit anti Human FOXO3A (MBS224281))
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Uniprot Description
FOXO3A: a transcription factors of the forkhead family. Contains 1 fork-head domain. May regulate apoptosis through control of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.
Protein type: Oncoprotein; Autophagy; Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: nucleoplasm; membrane; cytoplasm; nucleus; cytosol
Molecular Function: protein binding; DNA binding; chromatin DNA binding; sequence-specific DNA binding; transcription factor activity; protein kinase binding
Biological Process: epidermal growth factor receptor signaling pathway; transcription from RNA polymerase II promoter; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; DNA damage response, signal transduction by p53 class mediator; nerve growth factor receptor signaling pathway; initiation of primordial ovarian follicle growth; antral ovarian follicle growth; positive regulation of transcription, DNA-dependent; positive regulation of erythrocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; ovulation from ovarian follicle; glucose homeostasis; oocyte maturation; regulation of transcription from RNA polymerase II promoter; regulation of translation; positive regulation of neuron apoptosis; innate immune response; positive regulation of transcription from RNA polymerase II promoter
Research Articles on FOXO3A
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Product Notes
The FOXO3A foxo3 (Catalog #AAA224281) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI FOXO3A reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FOXO3A can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, ELISA (EIA), Western Blot (WB). ELISA: This product is suitable for use in indirect ELISA applications. Western Blot: This item detects a band of approximately 96 kDa in A-20 cell lysates. Immunohistology - Frozen: Minimum Dilution: 4ug/ml Western Blotting: Minimum Dilution: 0.5-1ug/ml. Researchers should empirically determine the suitability of the FOXO3A foxo3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXO3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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