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Western Blot (WB) (Western blot analysis of FOXL1 Antibody (Center) in CHO cell line lysates (35ug/lane).FOXL1 (arrow) was detected using the purified Pab;)

Rabbit anti-Human, Mouse FOXL1 Polyclonal Antibody | anti-FOXL1 antibody

FOXL1, ID (FOXL1, FKHL11, FREAC7, Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7) (APC)

Gene Names
FOXL1; FKH6; FKHL11; FREAC7
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
FOXL1; Polyclonal Antibody; ID (FOXL1; FKHL11; FREAC7; Forkhead box protein L1; Forkhead-related protein FKHL11; Forkhead-related transcription factor 7) (APC); Forkhead-related transcription factor 7; anti-FOXL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-FOXL1 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
FOXL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99~129 amino acids from the Center region of human FOXL1.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of FOXL1 Antibody (Center) in CHO cell line lysates (35ug/lane).FOXL1 (arrow) was detected using the purified Pab;)

Western Blot (WB) (Western blot analysis of FOXL1 Antibody (Center) in CHO cell line lysates (35ug/lane).FOXL1 (arrow) was detected using the purified Pab;)

Western Blot (WB)

(Western blot analysis of FOXL1 Antibody (Center) in mouse kidney tissue lysates (35ug/lane).FOXL1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of FOXL1 Antibody (Center) in mouse kidney tissue lysates (35ug/lane).FOXL1 (arrow) was detected using the purified Pab.)
Related Product Information for anti-FOXL1 antibody
The forkhead domain is a 100-amino acid monomeric DNA binding motif originally identified as a region of homology between the Drosophila forkhead protein and rat HNF3. Pierrou et al. (1994) identified 7 human genes containing forkhead domains and designated them forkhead related activators (FREAC) 1 through 7.
Product Categories/Family for anti-FOXL1 antibody
References
Rivadeneira, F., et.al., Nat. Genet. 41 (11), 1199-1206 (2009). Ferrell, R.E., et.al., Lymphat Res Biol 6 (2), 69-76 (2008). Hassel, S., et.al., Proteomics 4 (5), 1346-1358 (2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,490 Da
NCBI Official Full Name
forkhead box protein L1
NCBI Official Synonym Full Names
forkhead box L1
NCBI Official Symbol
FOXL1
NCBI Official Synonym Symbols
FKH6; FKHL11; FREAC7
NCBI Protein Information
forkhead box protein L1; forkhead-like 11; forkhead-related protein FKHL11; forkhead-related transcription factor 7
UniProt Protein Name
Forkhead box protein L1
Protein Family
UniProt Gene Name
FOXL1
UniProt Synonym Gene Names
FKHL11; FREAC7; FREAC-7
UniProt Entry Name
FOXL1_HUMAN

NCBI Description

This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]

Uniprot Description

FOXL1: Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; DNA bending activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; organ morphogenesis; multicellular organismal development; heart development; proteoglycan biosynthetic process; regulation of Wnt receptor signaling pathway; visceral mesoderm-endoderm interaction involved in midgut development

Research Articles on FOXL1

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Product Notes

The FOXL1 foxl1 (Catalog #AAA6299862) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOXL1, ID (FOXL1, FKHL11, FREAC7, Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7) (APC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FOXL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:50-100 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the FOXL1 foxl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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