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Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using FN3KRP antibody.)

Rabbit FN3KRP Polyclonal Antibody | anti-FN3KRP antibody

FN3KRP Polyclonal Antibody

Gene Names
FN3KRP; FN3KL
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
FN3KRP; Polyclonal Antibody; FN3KRP Polyclonal Antibody; FN3KL; anti-FN3KRP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
FN3KRP polyclonal antibody detects endogenous levels of FN3KRP protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
309
Applicable Applications for anti-FN3KRP antibody
Western Blot (WB)
Application Notes
WB: 1:200-1:2000
Immunogen
Recombinant protein of human FN3KRP
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using FN3KRP antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using FN3KRP antibody.)
Related Product Information for anti-FN3KRP antibody
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 35kDa
NCBI Official Full Name
ketosamine-3-kinase
NCBI Official Synonym Full Names
fructosamine 3 kinase related protein
NCBI Official Symbol
FN3KRP
NCBI Official Synonym Symbols
FN3KL
NCBI Protein Information
ketosamine-3-kinase
UniProt Protein Name
Ketosamine-3-kinase
Protein Family
UniProt Gene Name
FN3KRP
UniProt Synonym Gene Names
FN3K-RP; FN3K-related protein
UniProt Entry Name
KT3K_HUMAN

NCBI Description

A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

Uniprot Description

FN3KRP: Phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein- bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation. Belongs to the fructosamine kinase family.

Protein type: Kinase, other; EC 2.7.1.-

Chromosomal Location of Human Ortholog: 17q25.3

Molecular Function: kinase activity

Biological Process: phosphorylation

Research Articles on FN3KRP

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Product Notes

The FN3KRP fn3krp (Catalog #AAA3010580) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FN3KRP Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FN3KRP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:2000. Researchers should empirically determine the suitability of the FN3KRP fn3krp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FN3KRP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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