Immunohistochemistry (IHC)
(Anti-FMNL1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Human FMNL1 Polyclonal Antibody | anti-FMNL1 antibody
Rabbit Polyclonal to Human FMNL1
Usage: FRL1 antibody can be used for detection of FRL1 by Western blot at 1-2 ug/mL.
Immunohistochemistry (IHC)
(Anti-FMNL1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-FMNL1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunofluorescence (IF)
(Immunofluorescence of FRL1 in EL4 cells. Antibody concentration used was 20 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of FRL1 in EL4 cells. Antibody concentration used was 20 ug/ml.)
Western Blot (WB)
(Western blot analysis of FRL1 in EL4 cell lysate with FRL1 antibody at 1 ug/ml.)
Western Blot (WB)
(Western blot analysis of FRL1 in EL4 cell lysate with FRL1 antibody at 1 ug/ml.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
FMNL1: May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17q21
Cellular Component: membrane; plasma membrane; cell cortex; phagocytic vesicle; cytosol
Molecular Function: actin filament binding; protein binding; Rac GTPase binding; GTPase activating protein binding; profilin binding
Biological Process: substrate-bound cell migration; regulation of cell shape; actin filament severing; cortical actin cytoskeleton organization and biogenesis
Research Articles on FMNL1
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Product Notes
The FMNL1 fmnl1 (Catalog #AAA248361) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human FMNL1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FMNL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (5 ug/ml), WB (1 - 2 ug/ml) Usage: FRL1 antibody can be used for detection of FRL1 by Western blot at 1-2 ug/mL. Researchers should empirically determine the suitability of the FMNL1 fmnl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FMNL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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