Rabbit FLK1 Polyclonal Antibody | anti-kdrl antibody

Anti-FLK1 (Vascular Endothelial Growth Factor Receptor 2, VEGFR-2, Fetal Liver Kinase 1, FLK-1, Kinase NYK, Protein-tyrosine Kinase Receptor flk-1, CD309, Kdr, Flk-1, Flk1)

Cat. Num. AAA630950

• Gene Names: kdrl; flk; kdr; flk1; kdra; flk-1; vegr2; vegfr2; vegfr4; fk52c05; vegfr-2; MGC158203; wu:fk52c05
• Reactivity: Human; Mouse; Rat
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Affinity Purified
• Synonyms: FLK1; Polyclonal Antibody; Anti-FLK1 (Vascular Endothelial Growth Factor Receptor 2; VEGFR-2; Fetal Liver Kinase 1; FLK-1; Kinase NYK; Protein-tyrosine Kinase Receptor flk-1; CD309; Kdr; Flk-1; Flk1); Vascular Endothelial Growth Factor Receptor 2; Flk1; anti-kdrl antibody

• Host: Rabbit
• Reactivity: Human; Mouse; Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse FLK1. Species Crossreactivity: rat and human.
• Purity/Purification: Affinity Purified
• Form/Format: Supplied as a liquid in PBS, 0.1% BSA.
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-kdrl antibody: ELISA; Western Blot; Immunohistochemistry
• Application Notes: Suitable for use in Western Blot, ELISA, and Immunohistochemistry.; Recommended Dilutions: Western Blot: 1:1200-1:500 (Chemiluminescence); ELISA: 1:10,000-1:100,000; 50-100ng of control peptide/well; Immunohistochemistry: 2-20ug/ml
• Immunogen: Synthetic peptide corresponding to 20aa of mouse FLK1, C-terminal, Cytoplasmic domain (KLH).
• Source Information: Mouse
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.; Shipping Temperature: Blue Ice

Related Product Information for anti-kdrl antibody

Embryonic vascular system undergoes a series of complex, highly regulated series of events involving differentiation, migration and association of primitive endothelial cells. This process is termed vasculogenesis. A further remodeling of the primitive vascular system forms the mature cardiovascular system. This process is known as angiogenesis (sprouting of new capillary vessels from pre-existing vasculature). Study of tumor angiogenesis has led to the identification of several proteins including basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF). VEGF acts by interacting with a family of largely endothelial-specific receptor tyrosine kinases that includes VEGFR-1 (flt-1 or fms-like tyrosine kinase 1), VEGFR-2 (flk-1 or fetal liver kinase-1/KDR or Kinase insert domain containing receptor), and VEGFR-3/Flt-4. Disruption of VEGFRs interferes with differentiation of endothelial cells and it is lethal for the embryo.

Product Categories/Family for anti-kdrl antibody

Abs to Receptor Tyrosine Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 24181844
• NCBI GeneID: 796537
• UniProt Accession #: Q8AXB3; O42377; P79743; Q8UUW9; Q98891; Q9PTL0; A1L1P1; B0R127
• Molecular Weight: 146,950 Da
• NCBI Official Full Name: flk1
• NCBI Official Synonym Full Names: kinase insert domain receptor like
• NCBI Official Symbol: kdrl
• NCBI Official Synonym Symbols: flk; kdr; flk1; kdra; flk-1; vegr2; vegfr2; vegfr4; fk52c05; vegfr-2; MGC158203; wu:fk52c05
• NCBI Protein Information: vascular endothelial growth factor receptor kdr-like; VEGFR-4; fetal liver kinase 1; kinase insert domain receptor-A; kinase insert domain receptor-like; protein-tyrosine kinase receptor flk-1; vascular endothelial growth factor receptor 4; vascular endothelial growth factor receptor type 2
• UniProt Protein Name: Vascular endothelial growth factor receptor kdr-like
• Protein Family: Vascular endothelial growth factor receptor
• UniProt Gene Name: kdrl
• UniProt Synonym Gene Names: flk; flk-1; flk1; flka; kdr; kdra; vegfr2; vegfr4; vegr2
• UniProt Entry Name: VGFR4_DANRE