Rabbit anti-Human, Mouse FLJ23356 Polyclonal Antibody | anti-FLJ23356 antibody

FLJ23356 (SGK196, Probable Inactive Protein Kinase-like Protein SgK196, Sugen Kinase 196, MGC126597) (Biotin)

Cat. Num. AAA6378693

• Gene Names: POMK; SGK196; MDDGA12; MDDGC12
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: FLJ23356; Polyclonal Antibody; FLJ23356 (SGK196; Probable Inactive Protein Kinase-like Protein SgK196; Sugen Kinase 196; MGC126597) (Biotin); anti-FLJ23356 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human FLJ23356. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 350

• Applicable Applications for anti-FLJ23356 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human FLJ23356, aa1-350 (NP_115613.1).
• Immunogen Sequence: MEKQPQNSRRGLAPREVPPAVGLLLIMALMNTLLYLCLDHFFIAPRQSTVDPTHCPYGHFRIGQMKNCSPWLSCEELRTEVRQLKRVGEGAVKRVFLSEWKEHKVALSQLTSLEMKDDFLHGLQMLKSLQGTHVVTLLGYCEDDNTMLTEYHPLGSLSNLEETLNLSKYQNVNTWQHRLELAMDYVSIINYLHHSPVGTRVMCDSNDLPKTLSQYLLTSNFSILANDLDALPLVNHSSGMLVKCGHRELHGDFVAPEQLWPYGEDVPFHDDLMPSYDEKIDIWKIPDISSFLLGHIEGSDMVRFHLFDIHKACKSQTPSERPTAQDVLETYQKVLDTLRDAMMSQAREML
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SGK196 rabbit polyclonal antibody. Western Blot analysis of SGK196 expression in mouse liver.)

Western Blot (WB)

(Western Blot analysis of SGK196 expression in transfected 293T cell line by SGK196 polyclonal antibody. Lane 1: FLJ23356 transfected lysate (40kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-FLJ23356 antibody

SGK196 belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily

Product Categories/Family for anti-FLJ23356 antibody

Antibodies; Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 14149946
• NCBI GeneID: 84197
• NCBI Accession #: NP_115613.1
• NCBI GenBank Nucleotide #: NM_032237.2
• UniProt Accession #: Q9H5K3
• NCBI Official Full Name: protein O-mannose kinase
• NCBI Official Synonym Full Names: protein O-mannose kinase
• NCBI Official Symbol: POMK
• NCBI Official Synonym Symbols: SGK196; MDDGA12; MDDGC12
• NCBI Protein Information: protein O-mannose kinase
• UniProt Protein Name: Protein O-mannose kinase
• UniProt Gene Name: POMK
• UniProt Synonym Gene Names: SGK196; POMK
• UniProt Entry Name: SG196_HUMAN

NCBI Description

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Uniprot Description

POMK: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.

Protein type: EC 2.7.1.183; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; Protein kinase, Other; Membrane protein, integral; Kinase, protein; Other group; Other-Unique family

Chromosomal Location of Human Ortholog: 8p11.21

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: ATP binding; carbohydrate kinase activity; phosphotransferase activity, alcohol group as acceptor; protein kinase activity

Biological Process: brain development; carbohydrate phosphorylation; learning and/or memory; neuromuscular process; neuron migration; protein amino acid O-linked glycosylation; protein amino acid phosphorylation; sensory perception of pain

Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 12; Muscular Dystrophy-dystroglycanopathy (limb-girdle), Type C, 12